Results 71 to 80 of about 142,782 (274)

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Appointment scheduling model in healthcare using clustering algorithms

, 2020
In this study we provided a scheduling procedure which is combination of machine learning and mathematical programming. Outpatients who request for appointment in healthcare facilities have different priorities.
Hasankhani, Farhad, Kiani, Mahsa, Yousefi, Nooshin   +2 more
core  

The Veterans Health Administration: Implementing Patient-Centered Medical Homes in the Nation's Largest Integrated Delivery System [PDF]

, 2011
Describes the implementation of a model that organizes care around an interdisciplinary team of providers who work to identify and remove barriers to access and clinical effectiveness in primary care clinics.
Sarah Klein
core  

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Identifying key variables for designing a scheduling system for outpatient appointments: A systematic review

Payesh, 2017
Objective (s): The aim of this study was to assess dimensions and application of outpatient appointment systems. Methods: A systematic review was performed to indicate main factors affecting the performance of outpatient scheduling systems.
Afsoon Aeenparast, Maryam kheirandish, Farzaneh Maftoon, Faranak Farzadi   +3 more
doaj  

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Off-peak truck deliveries at container terminals: the 'Good Night' program in Israel [PDF]

, 2016
Purpose – Avoiding truck congestion and peaks in landside activity is one of the challenges to container terminal managers. The spreading of truck arrivals at terminals can be facilitated by widening the opening hours of terminals at the landside. Israel’
Bentolila, David, Hayuth, Yehuda, Kastro Ziedenveber, Ronit, Notteboom, Theo   +3 more
core   +1 more source

Stakeholders’ experiences, perceptions and satisfaction with an electronic appointment system: a qualitative content analysis

BMC Health Services Research
Background Online appointment scheduling systems have been designed and implemented to address barriers and problems related to in-person appointment scheduling; however, these systems also face challenges and issues that require continuous evaluation ...
Faezeh Ostadmohammadi, Ehsan Nabovati, Fatemeh Rangraze Jeddi, Leila Shokrizadeh Arani   +3 more
doaj   +1 more source

Data Analytics and Modeling for Appointment No-show in Community Health Centers

Journal of Primary Care & Community Health, 2018
Objectives: Using predictive modeling techniques, we developed and compared appointment no-show prediction models to better understand appointment adherence in underserved populations.
Iman Mohammadi, Huanmei Wu, Ayten Turkcan, Tammy Toscos, Bradley N. Doebbeling   +4 more
doaj   +1 more source