Results 71 to 80 of about 26,383 (257)

Appointment Scheduling with Delay Tolerance Heterogeneity

open access: yesINFORMS Journal on Computing
In this study, we investigate an appointment sequencing and scheduling problem with heterogeneous user delay tolerances under service time uncertainty. We aim to capture the delay tolerance effect with heterogeneity, in an operationally effective and computationally tractable fashion, for the appointment scheduling problem.
Shuming Wang   +3 more
openaire   +4 more sources

Automating NL appointment scheduling with COSMA [PDF]

open access: yesProceedings of the fifth conference on Applied natural language processing Descriptions of system demonstrations and videos -, 1997
Appointment scheduling is a problem faced daily by many individuals and organizations. Cooperating agent systems have been developed to partially automate this task. In order to extend the circle of participants as far as possible we advocate the use of natural language transmitted by e-mail.
openaire   +1 more source

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

Missed appointment in rabies vaccination schedule [PDF]

open access: yesArquivos de Neuro-Psiquiatria, 2012
Rabies is an important fatal neurological infection. The infection is due to the animal bite, especially dog bite. There is no specific treatment. It is suggested that vaccination is the best method for prevention rabies in the patients getting animal bite.
openaire   +5 more sources

The ubiquitin system in normal and infected germinal center B cells

open access: yesFEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis   +2 more
wiley   +1 more source

Data Analytics and Modeling for Appointment No-show in Community Health Centers

open access: yesJournal of Primary Care & Community Health, 2018
Objectives: Using predictive modeling techniques, we developed and compared appointment no-show prediction models to better understand appointment adherence in underserved populations.
Iman Mohammadi   +4 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

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