Results 151 to 160 of about 141,145 (350)

Multi-period appointment planning and scheduling in healthcare

, 2020
Randevu planlaması ve çizelgelemesi, hastalara verilen hizmetin kalitesinde ve önemli kaynakların verimli kullanılabilmesinde çok büyük rol oynar. Bu çalışmada, bir ayakta tedavi polikliniğinde, birden çok dönem için planlama ve çizelgeleme kararlarını beraber ele alan, iki aşamalı stokastik programlama modeli kullanılmıştır.
openaire   +1 more source

Maternal Preconception Antibiotic Exposure Disrupts Microbial Succession: A Transgenerational Risk for Offspring Gut Mucosal Immaturity and Colitis Susceptibility

Advanced Science, EarlyView.
This study reveals that maternal antibiotic exposure prior to conception disrupts intergenerational gut microbial succession. By enhancing maternal‐offspring microbial transmission, altering microbial developmental trajectories and increasing selective pressures during community assembly, these disturbances lead to persistent gut mucosal immaturity and
Yuzhu Chen, Ruqiao Duan, Cunzheng Zhang, Gaonan Li, XiaoLin Ji, Qi Zhang, Fei Pei, Kun Wang, Liping Duan   +8 more
wiley   +1 more source

Decision-making for pediatric vaccination scheduling under multiple constraints: a case study from China^✰. [PDF]

Front Public Health
Ma X, Huang Q, Chai S, Zhang M.
europepmc   +1 more source

Highly Active Cu14 Cluster Precisely Activates Autophagy Inhibitor to Amplify Cuproptosis Immunotherapy

Advanced Science, EarlyView.
An atomically precise Cu14 cluster‐mediated bond scission reaction pioneers the amplification of the antitumor immune response via synergetic cuproptosis‐associated immunogenic cell death induction and in situ autophagy blockade. ABSTRACT Transition metal‐mediated cleavage mechanisms have emerged as an effective means to mitigate the off‐target ...
Qiu‐Xu Zang, Wei‐Tong Chen, Yu‐Ying Shen, Zhao‐Yang Wang, Kai Li, Xueli Zhao, Yanjuan Sang, Xiaoyuan Chen, Shuang‐Quan Zang   +8 more
wiley   +1 more source

Bridging HIV prevention and sexual reproductive health services in the context of multi-method PrEP: a qualitative study exploring provider perceptions in South Africa. [PDF]

Front Reprod Health
Musvipwa FM, Dada S, Cholo FA, Pleaner M, Letsielo MJ, Arries S, Kutywayo A, Martin CE, Mullick S.   +8 more
europepmc   +1 more source

Appointment Overbooking in Health Care Clinics to Improve Patient Service and Clinic Performance

, 2012
Linda R. LaGanga, S. Lawrence
semanticscholar   +1 more source

Hierarchical Targeting of TREM2+ Myeloid Cells via Acid‐Triggered OMVs Reprogram Immunosuppression and Suppress Osteolysis in Bone‐Metastatic TNBC

Advanced Science, EarlyView.
This study developed a hierarchical targeting nanoplatform, siTREM2@ETP‐PEOz‐OMVs, against triple‐negative breast cancer (TNBC) bone metastasis. It precisely delivers therapeutic siTREM2 to monocytes/macrophages within the metastatic niche. This intervention dually regulates cell fate: reprogramming immunosuppressive macrophages and inhibiting ...
Fanglu Chen, Yucheng Xue, Xiao Ma, Liang Chen, Zhenxuan Shao, Hangxiang Sun, Haochen Mou, Fangqian Wang, Zilong Li, Yechao Shen, Zhaoming Ye, Xiaohua Yu, Shengdong Wang   +12 more
wiley   +1 more source

Abbott Union Free School District and Abbott School Teachers Association (2009) [PDF]

, 2009

core   +1 more source

Engineered Bacteria Factory Integrating Drug Delivery and Antibody Manufacture for Activating the STING Signal Pathway Mediated Tumor Immunotherapy

Advanced Science, EarlyView.
To address the limitations of protein‐based ICIs in applications, this study constructed an engineered bacterium, HRB, capable of expressing aCD47 in hypoxic TME. Through the Schiff base reaction, responsive liposomes (LC) loaded with the STING agonist cGAMP were connected to the surface of bacteria to form HRB@LC.
Peng‐Shuo Dong, Tian Yao, Yong Li, Zi‐Hui Yan, Xiao‐Ting Xie, Jia‐Hua Zou, Kai Cheng, Jin‐Xuan Fan, Yuan‐Di Zhao, Qiu‐Ran Xu   +9 more
wiley   +1 more source

Building bridges: the integral presence of audiologists and speech-language pathologists in comprehensive interprofessional primary care teams. [PDF]

Prim Health Care Res Dev
Alaniz G, Bataineh J, O'Hagan R, Moodie S, Pichora-Fuller M, Cameron-Turley J, Cooke B, Carey A, Orange JB, Cooper M, Glista D.   +10 more
europepmc   +1 more source