Efficacy of Inebilizumab in N‐MOmentum Trial Participants With or Without Prior Immunosuppressants
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT This post hoc analysis examined the impact of prior immunosuppressants on the long‐term efficacy and safety of inebilizumab, a cluster of differentiation 19+ B‐cell–depleting monoclonal antibody, in participants with aquaporin‐4–seropositive neuromyelitis optica spectrum disorder from the N‐MOmentum trial (NTC02200770).
Bruce A. C. Cree +9 more
wiley +1 more source
No Significant Difference Is Not Equivalence: Statistical Considerations on Phenylephrine Requirement in Left-Tilt versus Supine Cesarean Delivery [Response to Letter]. [PDF]
Drug Des Devel TherYu XQ, Xiao F.
europepmc +1 more source
Metabolic and Microvascular Risk Factors Associated With Brain Health in Type 1 Diabetes
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT We examined relationships between metabolic factors, microvascular complications, and brain health in adults with type 1 diabetes. Fifty‐one adults were assessed for metabolic risk factors, microvascular complications, and cognitive function, with a subset completing brain MRI.
Jihyun Park +7 more
wiley +1 more source
The Mediating Effect of Body Appreciation on the Association Between Undiagnosed Polycystic Ovary Syndrome (PCOS) and Eating Disorders: A Cross-Sectional Study Among Lebanese Women. [PDF]
Int J Womens HealthEl Achkar N +8 more
europepmc +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Digital technologies hold promise for transforming healthcare by enhancing personalized treatments and offer valuable opportunities to improve patient care. Here, we evaluated several novel, self‐administered, home‐based, digital endpoints for their association with corresponding conventional standard clinical measures (primary) in ...
Arne Mueller +14 more
wiley +1 more source
Art-based beauty appreciation intervention in young adults: protocol for a two-arm active control mixed-method randomised controlled trial (ABBA-Vention). [PDF]
TrialsTrupp MD +6 more
europepmc +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw +5 more
wiley +1 more source
Psychometric properties of the Post-Traumatic Growth Inventory-Short Form (PTGI-SF) in Chilean population exposed to the February 27th earthquake: analysis through Exploratory Structural Equation Modeling. [PDF]
Front PsycholSerrano C +5 more
europepmc +1 more source