Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Comparative analysis of endoscopic endonasal far-medial, far-lateral transcondylar and combined approaches to the foramen magnum region: volumetric analysis and quantitative insights on surgical exposure and maneuverability. [PDF]
Blue R +7 more
europepmc +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
International Humanitarian Assistance and International Law
Emilie E. Kuijt, Stefanie Jansen-Wilhelm
doaj +1 more source
A haplotype-based approach to explore genotype-by-environment interactions for barley yield. [PDF]
Brunner SM +9 more
europepmc +1 more source
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Nearly Two Decades of Sustaining a Coalition to Prevent Youth Substance Use: Reflections From the Genesee County Prevention Coalition, Michigan. [PDF]
Fockler L +3 more
europepmc +1 more source
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Introduction: As part of the path toward a sugarcane biorefinery scheme, it is necessary to study the utilization of byproducts such as sugarcane filter cake and vinasse, particularly as energy sources through their anaerobic conversion to biomethane ...
Carlos Loyo-Inclán +5 more
doaj
Surgical approach and insert constraint are associated with small differences in patellar tilt after robotic-assisted total knee arthroplasty: A retrospective comparative radiographic study. [PDF]
Favroul C +4 more
europepmc +1 more source

