Results 1 to 10 of about 27,114,064 (337)

The human gut microbiota contributes to type-2 diabetes non-resolution 5-years after Roux-en-Y gastric bypass

open access: yesGut Microbes, 2022
Roux-en-Y gastric bypass (RYGB) is efficient at inducing drastic albeit variable weight loss and type-2 diabetes (T2D) improvements in patients with severe obesity and T2D.
Jean Debédat   +19 more
doaj   +1 more source

A deep-learning approach for online cell identification and trace extraction in functional two-photon calcium imaging

open access: yesNature Communications, 2022
Processing of two-photon calcium imaging data is generally time-consuming, especially for large fields of view. Here, the authors present CITE-On, a tool based on a convolutional neural network, enabling online automatic cell identification, segmentation,
Luca Sità   +6 more
doaj   +1 more source

Latent dirichlet allocation for double clustering (LDA-DC): discovering patients phenotypes and cell populations within a single Bayesian framework

open access: yesBMC Bioinformatics, 2023
Background Current clinical routines rely more and more on “omics” data such as flow cytometry data from host and microbiota. Cohorts variability in addition to patients’ heterogeneity and huge dimensions make it difficult to understand underlying ...
Elie-Julien El Hachem   +2 more
doaj   +1 more source

A curated gene and biological system annotation of adverse outcome pathways related to human health

open access: yesScientific Data, 2023
Adverse outcome pathways (AOPs) are emerging as a central framework in modern toxicology and other fields in biomedicine. They serve as an extension of pathway-based concepts by depicting biological mechanisms as causally linked sequences of key events ...
Laura Aliisa Saarimäki   +6 more
doaj   +1 more source

Functional alterations and predictive capacity of gut microbiome in type 2 diabetes

open access: yesScientific Reports, 2023
The gut microbiome plays a significant role in the development of Type 2 Diabetes Mellitus (T2DM), but the functional mechanisms behind this association merit deeper investigation. Here, we used the nanopore sequencing technology for metagenomic analyses
Nihar Ranjan Dash   +8 more
doaj   +1 more source

Knowledge management of pomelo production system in Northeast Thailand: A case study of the pomelo farmer group in Ban Thaen district [PDF]

open access: yesForest and Society, 2018
In Thailand pomelo is a fruit tree that has long been grown in the central region particularly in Nakhon Chai Si district, Nakhon Pathom province where soil is relatively fertile and has conditions of sufficient water resources.
Kanchana Duangta   +2 more
doaj   +1 more source

Terra incognita of vitality problem: Open issues. Part 1 [PDF]

open access: yesИзвестия Саратовского университета. Новая серия: Акмеология образования. Психология развития, 2021
The increase of uncertainty, instability, complexity, ambiguity of the dynamics of the condition of social subjects are among the issues that make vitality problem topical.
Vladimir A. Tolochek
doaj   +1 more source

Characterization of the Gut Microbiota in Individuals with Overweight or Obesity during a Real-World Weight Loss Dietary Program: A Focus on the Bacteroides 2 Enterotype

open access: yesBiomedicines, 2021
Background: Dietary intervention is a cornerstone of weight loss therapies. In obesity, a dysbiotic gut microbiota (GM) is characterized by high levels of Bacteroides lineages and low diversity.
Rohia Alili   +9 more
doaj   +1 more source

The essence of economic security of entrepreneurial activities [PDF]

open access: yesЕкономічний вісник Державного вищого навчального закладу Український державний хіміко-технологічний університет, 2021
This paper focuses on approaches to defining the concept of economic security of an enterprise. One of the conditions for the sustainable development of business entities is the existence of an effective system for ensuring their economic security, which
D. Aniskevich
doaj   +1 more source

The Financial Strategies and Approaches of Chinese Government Towards the Internationalization of Higher Education in China [PDF]

open access: yesAmfiteatru Economic, 2020
Approaches of internationalization of higher education (HE) have stimulated numerous countries to concurrently formulating innovative policies and strategies to make their higher educational institutions (HEIs) globally competitive. This has the aim to
Frank Okai Larbi   +3 more
doaj   +1 more source

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