Results 231 to 240 of about 12,102,313 (285)

Transportability Analyses in Comparative Effectiveness Research: A Conceptual Framework and Methodological Principles Endorsed by the International Society for Pharmacoepidemiology. [PDF]

open access: yesPharmacoepidemiol Drug Saf
Adamson B   +11 more
europepmc   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

The Dynamic Approach

open access: yesInternational Journal of Orofacial Myology, 1979
openaire   +3 more sources

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

From Precision to Personalized: Catalyzing AI-Enabled Innovation in Drug Development. [PDF]

open access: yesClin Transl Sci
Subbaswamy A   +5 more
europepmc   +1 more source

Methodical approaches to assess innovation projects [PDF]

open access: yes, 2018
Kobielieva, T. O.   +2 more
core  

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