Results 51 to 60 of about 3,581,525 (255)
The Quantum Alternating Operator Ansatz on Maximum k-Vertex Cover [PDF]
The Quantum Alternating Operator Ansatz is a generalization of the Quantum Approximate Optimization Algorithm (QAOA) designed for finding approximate solutions to combinatorial optimization problems with hard constraints.
Jeremy Cook +2 more
semanticscholar +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Molecular bases of circadian magnesium rhythms across eukaryotes
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Uniform rectifiability and $\varepsilon$-approximability of harmonic functions in $L^p$
Suppose that $E \subset \mathbb{R}^{n+1}$ is a uniformly rectifiable set of codimension $1$. We show that every harmonic function is $\varepsilon$-approximable in $L^p(\Omega)$ for every $p \in (1,\infty)$, where $\Omega := \mathbb{R}^{n+1} \setminus E$.
Hofmann, Steve, Tapiola, Olli
core +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Provable ICA with Unknown Gaussian Noise, and Implications for Gaussian Mixtures and Autoencoders [PDF]
We present a new algorithm for Independent Component Analysis (ICA) which has provable performance guarantees. In particular, suppose we are given samples of the form $y = Ax + \eta$ where $A$ is an unknown $n \times n$ matrix and $x$ is a random ...
Arora, Sanjeev +3 more
core
In this paper, we apply the Daftardar-Jafari method (DJM) and Sumudu decomposition method (SDM) to obtain the approximate analytical solutions of the fractional system of differential equations with Caputo-Fabrizio fractional derivative operator.
Hassan Kamil Jassim +1 more
semanticscholar +1 more source
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Orthogonally additive polynomials on the algebras of approximable operators
Let $X$ and $Y$ be Banach spaces, let $\mathcal{A}(X)$ stands for the algebra of approximable operators on $X$, and let $P\colon\mathcal{A}(X)\to Y$ be an orthogonally additive, continuous $n$-homogeneous polynomial.
Alaminos, J. +2 more
core +1 more source

