Results 81 to 90 of about 3,581,525 (255)
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Approximation by Choquet integral operators [PDF]
Annali di Matematica Pura ed Applicata (1923 -), 2015 The main aim of this paper is to show that the nonlinear Choquet integral can be used to construct nonlinear approximation operators, exactly as by the use in probability of the Lebesgue-type integral, linear and positive approximation operators are constructed.
openaire +3 more sources
New Numerical Aspects of Caputo-Fabrizio Fractional Derivative Operator
Mathematics, 2019 In this paper, a new definition for the fractional order operator called the Caputo-Fabrizio (CF) fractional derivative operator without singular kernel has been numerically approximated using the two-point finite forward difference formula for the ...
S. Qureshi +2 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Information Complexity Ranking: A New Method of Ranking Images by Algorithmic Complexity. [PDF]
Entropy (Basel), 2023 Chambon T, Guillaume JL, Lallement J.
europepmc +1 more source
Approximation spaces for H-operators
Involve, a Journal of MathematicsThis paper defines and establishes relations among approximation spaces of certain operators called \textit{H-operators}, which generalize the notion of self-adjoint to Banach spaces.
Aksoy, Asuman Güven +1 more
openaire +2 more sources
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
A novel fractional discrete grey model with variable weight buffer operator and its applications in renewable energy prediction. [PDF]
Soft comput, 2023 Wang Y, Chi P, Nie R, Ma X, Wu W, Guo B.
europepmc +1 more source