Results 111 to 120 of about 5,991,687 (297)
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
A new multistage technique for approximate analytical solution of nonlinear differential equations. [PDF]
Heliyon, 2020 Akindeinde SO.
europepmc +1 more source
Highly Accurate Analytical Approximate Solution to a Nonlinear Pseudo-Oscillator
, 2017 A second-order Newton method is presented to construct analytical approximate solutions to a nonlinear pseudo-oscillator in which the restoring force is inversely proportional to the dependent variable.
Weijia Liu, C.W. Lim, Baisheng Wu
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Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Fractional calculus model for damped Mathieu equation: approximate analytical solution
, 2012 The classical damped Mathieu differential equation was firstly introduced by Mathieu in 1868 to determine the vibration modes of a stretched membrane having an elliptical clamped boundary.
Doaa M M Elsayed +2 more
core
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Approximate analytical solutions to conformable modified Burgers equation using homotopy analysis method [PDF]
, 2018 In this paper the authors aspire to obtain the approximate analytical solution of Modified Burgers Equation with newly defined conformable derivative by employing homotopy analysis method (HAM)
Tasbozan, Orkun, Kurt, Ali
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The analytical and approximate solutions of ϵy″ = yy′
Journal of Mathematical Analysis and Applications, 1983 AbstractThe analytical and approximate soluions of ϵy″ = yy′ are developed and compared, and the analytical solution is evaluated numerically. The analytical soluion has several interesting properties: (i) it possesses three different types of solutions, constant, exponential, and tangent; (ii) for a two-point boundary value problem it has an ...
openaire +1 more source