Results 141 to 150 of about 572,545 (279)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Analytical approximate solutions to the nonlinear Fornberg–Whitham type equations via modified variational iteration method

Partial Differential Equations in Applied Mathematics
In this paper, we utilize the modified variational iteration method introduced by Abassy et al. for obtaining the analytical approximate solutions of the nonlinear Fornberg–Whitham equation and modified nonlinear Fornberg–Whitham equation.
Md. Asaduzzaman, Faruk Özger, Adem Kilicman   +2 more
doaj   +1 more source

An approximate analytical solution of the Allen-Cahn equation using homotopy perturbation method and homotopy analysis method. [PDF]

Heliyon, 2019
Hussain S, Shah A, Ayub S, Ullah A.
europepmc   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

An approximate analytical solution of the Bethe equation for charged particles in the radiotherapeutic energy range. [PDF]

Sci Rep, 2017
Grimes DR, Warren DR, Partridge M.
europepmc   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Solving the Nonlinear Charged Particle Oscillation Equation Using the Laplace–Adomian Decomposition Method

Advances in Mathematical Physics
This manuscript presents a comprehensive exploration of the nonlinear charged particle oscillation equation, employing the Laplace–Adomian decomposition method (LDM) to obtain approximate analytical solutions.
Omar Alomari, Bashar F. Garalleh, Emad K. Jaradat, Behzad Omidi Koma   +3 more
doaj   +1 more source

Approximate analytic solutions of nonlinear integral equations

, 2021
Bu tezde doğrusal olmayan integral denklemler, doğrusal olmayan integral denklem sistemleri, integro-diferansiyel denklemler incelenmiş, bu denklemlerin çözümlerinin varlık ve tekliği Lipschitz sürekli çekirdekler için araştırılmıştır. Doğrusal olmayan integral denklemlerin ve denklem sistemlerinin çözümü için analitik bir yöntem olan He'nin ...
openaire   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source