Results 111 to 120 of about 808,804 (331)

Approximate Computing-Based Processing of MEA Signals on FPGA [PDF]

, 2023
Mohammad Hassan, Falah Awwad, Mohamed Atef, Osman Hasan   +3 more
openalex   +1 more source

Approximate Generalizations and Computational Experiments [PDF]

Econometrica, 2007
In this paper I demonstrate how one can generalize finitely many examples to statements about (infinite) classes of economic models. If there exist upper bounds on the number of connected components of one-dimensional linear subsets of the set of parameters for which a conjecture is true, one can conclude that it is correct for all parameter values in ...
openaire   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Data Dependence for Ishikawa Iteration When Dealing with Contractive-Like Operators

Fixed Point Theory and Applications, 2008
We prove a convergence result and a data dependence for Ishikawa iteration when applied to contraction-like operators. An example is given, in which instead of computing the fixed point of an operator, we approximate the operator with a contractive-like ...
Teodor Grosan, Ş. M. Şoltuz
doaj   +1 more source

Computation of Best Monotone Approximations [PDF]

Mathematics of Computation, 1972
A numerical procedure to compute the best uniform approximation to a given continuous function by algebraic polynomials with nonnegative r r th derivative is presented and analyzed. The method is based on discretization and linear programming. Several numerical experiments are discussed.
openaire   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

New insights into Approximate Bayesian Computation

Annales de l'Institut Henri Poincaré, Probabilités et Statistiques, 2015
Approximate Bayesian Computation (ABC for short) is a family of computational techniques which offer an almost automated solution in situations where evaluation of the posterior likelihood is computationally prohibitive, or whenever suitable likelihoods are not available.
Biau, Gérard, Cérou, Frédéric, Guyader, Arnaud   +2 more
openaire   +6 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

A Low-Power DNN Accelerator With Mean-Error-Minimized Approximate Signed Multiplier

IEEE Open Journal of Circuits and Systems
Approximate computing is an emerging and effective method for reducing energy consumption in digital circuits, which is critical for energy-efficient performance improvement of edge-computing devices. In this paper, we propose a low-power DNN accelerator
Laimin Du, Leibin Ni, Xiong Liu, Guanqi Peng, Kai Li, Wei Mao, Hao Yu   +6 more
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source