Results 111 to 120 of about 812,236 (286)

Approximate relations for laminar heat-transfer and shear-stress functions in equilibrium dissociated air [PDF]

Approximate equations for computing enthalpy and velocity derivatives at surface of flat plate, cone, or blunt axisymmetric ...
Zoby, E. V.
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

On the stability of displaced two-body lunar orbits [PDF]

, 2010
In a prior study, a methodology was developed for computing approximate large displaced orbits in the Earth-Moon circular restricted three-body problem (CRTBP)by the Moon-Sail two-body problem.
McInnes, Colin R., Simo, Jules
core  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Performance Improvement of Processor Through Configurable Approximate Arithmetic Units in Multicore Systems

IEEE Access
Multicore systems are utilized in a wide range of applications, from embedded systems to high-performance applications. Controlling power consumption while maximizing performance under the Thermal Design Power (TDP) becomes increasingly important when ...
Seyed Ali Kashani Gharavi, Saeed Safari
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

scaleTRIM: Scalable TRuncation-Based Integer Approximate Multiplier With Linearization and Compensation

IEEE Access
In this paper, we propose a scalable approximate multiplier design, scaleTRIM, that approximates the multiplication operation using fitted linear functions, also referred to as linearization.
Ebrahim Farahmand, Mohammad Javad Askarizadeh, Ali Mahani, Behnam Ghavami, Hassan Ghasemzadeh, Muhammad Abdullah Hanif, Muhammad Shafique   +6 more
doaj   +1 more source

Data Dependence for Ishikawa Iteration When Dealing with Contractive-Like Operators

Fixed Point Theory and Applications, 2008
We prove a convergence result and a data dependence for Ishikawa iteration when applied to contraction-like operators. An example is given, in which instead of computing the fixed point of an operator, we approximate the operator with a contractive-like ...
Teodor Grosan, Ş. M. Şoltuz
doaj   +1 more source

Approximate Generalizations and Computational Experiments [PDF]

Econometrica, 2007
In this paper I demonstrate how one can generalize finitely many examples to statements about (infinite) classes of economic models. If there exist upper bounds on the number of connected components of one-dimensional linear subsets of the set of parameters for which a conjecture is true, one can conclude that it is correct for all parameter values in ...
openaire   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source