Results 171 to 180 of about 808,804 (331)
Approximate Computing for Test and Test of Approximate Computing
Approximate Computing (AxC) is nowadays a well established design and computing paradigm to produce more efficient computation systems by judiciously reducing the computation quality. In particular, AxC has been successfully applied to Integrated Circuits (ICs), in the last years in both ways: AxC for test and the test of AxC integrated circuits.
Barbareschi, Mario +5 more
openaire +1 more source
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source
Matrix Padé approximation: Recursive computations
The authors consider the computational aspects of the matrix Padé approximants whose definition and properties were described by themselves earlier [Linear Algebra Appl. 137/138, 67-136 (1990; Zbl 0704.41011)]. Two theorems are proved and a recursive method is given for computing the approximants.
Xu, Gl, Bultheel, Adhemar
openaire +2 more sources
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Area efficient approximate multiplier based on novel 4:2 compressors and error correction logic. [PDF]
P KP, V NK.
europepmc +1 more source
Using Approximate Computing for the Calculation of Inverse Matrix p-th\n Roots [PDF]
Michael Laß +2 more
openalex +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
NISQ+: Boosting quantum computing power by approximating quantum error\n correction [PDF]
Adam Holmes +5 more
openalex +1 more source
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source

