Results 151 to 160 of about 3,779 (296)
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Optimal stochastic tracking control for brain network dynamics. [PDF]
Dong K +7 more
europepmc +1 more source
In this paper, fractional backward stochastic differential equations are extended to multivalued forms. Since the problem of approximate controllability of the obtained fractional backward stochastic differential inclusions has not yet been addressed in ...
selah, müberra
core +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Educational anxiety and student mental health in the era of artificial intelligence: a multi-source data fusion analysis in smart education. [PDF]
Tian Q.
europepmc +1 more source
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Existence and controllability analysis of multi-term fractional coupled systems with generalized [Formula: see text]-Caputo-Fabrizio operators. [PDF]
Saad KM, Abdo MS, Hamanah WM.
europepmc +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Evolution psi-Hilfer fractional differential equations in Banach spaces
This article concerns evolution equations involving $\psi$-Hilfer fractional derivative in a Banach space. By using the theory of fractional calculus and $\psi$-Laplace transform, we firstly derive a definition of mild solutions for these equations ...
Jin Liang, Yunyi Mu, Ti-Jun Xiao
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