Results 81 to 90 of about 38,188 (290)

Investigation of Differential Evolution Algorithm for a Tandem Cascade Optimization

open access: yesXibei Gongye Daxue Xuebao, 2019
Due to the fact that there are numerous factors and parameters associated to tandem cascade, and upstream and downstream blades have intensive interference and unknown matching correlation, it is difficult to create tandem blades with high performance ...

doaj   +1 more source

Approximation algorithms for maximum two-dimensional pattern matching [PDF]

open access: yesTheoretical Computer Science, 1996
We introduce the following optimization version of the classical pattern matching problem (referred to as the maximum pattern matching problem). Given a two-dimensional rectangular text and a two-dimensional rectangular pattern, find the maximum number of non-overlapping occurrences of the pattern in the text.
Arikati, S.R.   +3 more
openaire   +5 more sources

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Dynamic programming for reduced NFAs for approximate string and sequence matching [PDF]

open access: yes, 2002
summary:searching for all occurrences of a pattern (string or sequence) in some text, where the pattern can occur with some limited number of errors given by edit distance.
Holub, Jan
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

On the Communication Complexity of Approximate Pattern Matching

open access: yesProceedings of the 56th Annual ACM Symposium on Theory of Computing
67 pages; 5 figures; abstract ...
Tomasz Kociumaka   +2 more
openaire   +4 more sources

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Programmable Multiplexed Nucleic Acid Detection by Harnessing Specificity Defect of CRISPR‐Cas12a

open access: yesAdvanced Science
CRISPR‐Cas12a works like a sophisticated algorithm in nucleic acid detection, yet its challenge lies in sometimes failing to distinguish targets with mismatches due to its specificity limitations.
Xin Guan   +10 more
doaj   +1 more source

The Complexity of Approximate Pattern Matching on de Bruijn Graphs

open access: yes, 2022
Aligning a sequence to a walk in a labeled graph is a problem of fundamental importance to Computational Biology. For finding a walk in an arbitrary graph with $|E|$ edges that exactly matches a pattern of length $m$, a lower bound based on the Strong Exponential Time Hypothesis (SETH) implies an algorithm significantly faster than $O(|E|m)$ time is ...
Daniel Gibney   +2 more
openaire   +2 more sources

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

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