Pharmacologic MRI Brain Imaging Studies of Serotonin 5‐HT1 Receptor Agonists in Awake Mice
ABSTRACT Serotonin (5‐hydroxytryptamine, 5‐HT) type‐1 G protein‐coupled receptors are expressed throughout the central nervous system. 5‐HT1AR activation is the putative mechanism of approved drugs for generalized anxiety disorder and major depressive disorder and is being studied in the treatment of autism and neurological disorders.
Brittany M. Brems +5 more
wiley +1 more source
Photonic fully-connected hybrid beamforming using microring weight banks. [PDF]
Nichols M +4 more
europepmc +1 more source
Quantum Information Measures of a Dirichlet Waveguide with Neumann Window(s)
ABSTRACT Engineering boundary conditions in low‐dimensional structures provides a simple yet powerful way of shaping how quantum information is stored and transported. We investigate a flat 2D Dirichlet waveguide containing one or two finite Neumann windows and compute the bound states in both position and momentum space as functions of the window ...
Firoz Chogle, Berihu Teklu
wiley +1 more source
Exact hydrodynamic manifolds for the linear Boltzmann BGK equation I: spectral theory. [PDF]
Kogelbauer F, Karlin I.
europepmc +1 more source
Wasserstein Regression, Forecasting, and Change‐Point Detection for Daily Traffic Flow Distributions
ABSTRACT We develop a distribution‐valued framework for modeling, forecasting, and monitoring traffic flow counts by treating each day as a probability distribution summarized by jittered empirical quantile signatures. Inference is conducted under the 2‐Wasserstein geometry, which in one dimension is isometric to the L2(0,1)$$ {L}^2\left(0,1\right ...
Abdolnasser Sadeghkhani
wiley +1 more source
ABSTRACT Understanding the mechanisms through which anti‐cancer treatments influence survival is central to improving drug development and evaluation. In this work, we develop a Bayesian joint modeling framework for mediation analysis to quantify the extent to which tumor size dynamics mediate the effect of treatment on overall survival (OS). Our model
Georgios Kazantzidis +2 more
wiley +1 more source
Efficient High-Order Space-Angle-Energy Polytopic Discontinuous Galerkin Finite Element Methods for Linear Boltzmann Transport. [PDF]
Houston P +4 more
europepmc +1 more source
ABSTRACT Depicting patient transitions among multiple clinical states is a common objective in health services and epidemiological research. Multistate models (MSM) are the primary analytical approach used in such studies. Although the structure of an MSM is typically determined by the research questions of a specific application, models are typically ...
Jason Mao, Yang Li, Wanzhu Tu
wiley +1 more source
Near-field-free super-potential FFT method for the three-dimensional free-space Poisson equation
Exl L, Schaffer S.
europepmc +1 more source
Discontinuities of Kinetic Energy Densities within Finite and Complete Basis Sets. [PDF]
Moore CC, Staroverov VN.
europepmc +1 more source

