Results 111 to 120 of about 2,095,948 (338)

False Approximations of the Approximate Number System?

open access: yesPLoS ONE, 2011
Prior research suggests that the acuity of the approximate number system (ANS) predicts future mathematical abilities. Modelling the development of the ANS might therefore allow monitoring of children's mathematical skills and instigate educational intervention if necessary.
Gebuis, T., Van der Smagt, M.J.
openaire   +5 more sources

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

ON ENTIRE FUNCTIONS WITH GIVEN ASYMPTOTIC BEHAVIOR

open access: yesПроблемы анализа, 2018
We study approximation of subharmonic functions on the complex plane by logarithms of moduli of entire functions. In the theory of series of exponentials these entire functions are the main tool.
Isaev K . P .
doaj   +1 more source

Approximate continuity and linear approximate continuity [PDF]

open access: yesProceedings of the American Mathematical Society, 1993
A contrast between approximated continuity and continuity is obtained similar to the classical one for derivatives.
openaire   +1 more source

Linear stationary iterative methods for the force-based quasicontinuum approximation [PDF]

open access: yes, 2012
Force-based multiphysics coupling methods have become popular since they provide a simple and efficient coupling mechanism, avoiding the difficulties in formulating and implementing a consistent coupling energy.
Luskin, Mitchell Barry   +1 more
core   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Stability, instability, and error of the force-based quasicontinuum approximation [PDF]

open access: yes, 2009
Due to their algorithmic simplicity and high accuracy, force-based model coupling techniques are popular tools in computational physics. For example, the force-based quasicontinuum (QCF) approximation is the only known pointwise consistent quasicontinuum
Luskin, Mitchell Barry   +5 more
core   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Lower bounds for the low-rank matrix approximation

open access: yesJournal of Inequalities and Applications, 2017
Low-rank matrix recovery is an active topic drawing the attention of many researchers. It addresses the problem of approximating the observed data matrix by an unknown low-rank matrix. Suppose that A is a low-rank matrix approximation of D, where D and A
Jicheng Li, Zisheng Liu, Guo Li
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

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