Results 111 to 120 of about 545,451 (275)
Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky +8 more
wiley +1 more source
Second Order Filter Distribution Approximations for Financial Time Series with Extreme Outliers [PDF]
Particle Filters are now regularly used to obtain the filter distributions associated with state space financial time series. Most commonly used nowadays is the auxiliary particle filter method in conjunction with a first order Taylor expansion of the ...
António Santos, J. Q. Smith
core
Abstract and Applied Analysis, 2014 A method for the approximate computation of frequency-dependent magnetic and electric matrix Green’s functions in a rectangular parallelepiped with a perfect conducting boundary is suggested in the paper.
V. G. Yakhno, Ş. Ersoy
doaj +1 more source
Shared Genetic Effects and Antagonistic Pleiotropy Between Multiple Sclerosis and Common Cancers
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Epidemiologic studies have reported inconsistent altered cancer risk in individuals with multiple sclerosis (MS). Factors such as immune dysregulation, comorbidities, and disease‐modifying therapies may contribute to this variability.
Asli Buyukkurt +5 more
wiley +1 more source
Expansion of Brownian Motion Functionals and Its Application in Econometric Estimation [PDF]
Two types of Brownian motion functionals, both time-homogeneous and time-inhomogeneous, are expanded in terms of orthonormal bases in respective Hilbert spaces. Meanwhile, different time horizons are treated from the applicability point of view. Moreover,
Chaohua Dong, Jiti Gao
core
, 2012 In this short note we show the equivalence of Fourier expansion and Poisson summation approaches for the series approximation of the exponential function $\exp ({-{t^2}/4})$. The application of the Poisson summation formula is shown to reduce to that of the Fourier expansion method.
Abrarov, S. M. +2 more
openaire +2 more sources
Identification of Dynamic Loads Based on Second-Order Taylor-Series Expansion Method
Shock and Vibration, 2016 A new method based on the second-order Taylor-series expansion is presented to identify the structural dynamic loads in the time domain. This algorithm expresses the response vectors as Taylor-series approximation and then a series of formulas are ...
Xiaowang Li, Zhongmin Deng
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu +10 more
wiley +1 more source
Arthritis Care &Research, EarlyView.Objective In complex diseases, it is challenging to assess a patient's disease state, trajectory, treatment exposures, and risk of multiple outcomes simultaneously, efficiently, and at the point of care. Methods We developed an interactive patient‐level data visualization and analysis tool (VAT) that automates illustration of the trajectory of a ...
Ji Soo Kim +18 more
wiley +1 more source
Injection into Orbit Optimization using Orthogonal Polynomials [PDF]
International Journal of Advanced Design and Manufacturing Technology, 2017 In this study, the problem of determining an optimal trajectory of a nonlinear injection into orbit problem with minimum time was investigated. The method was based on orthogonalpolynomial approximation.
Sedigheh Shahmirzaee Jeshvaghany +2 more
doaj