Results 91 to 100 of about 227,595 (269)

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Synthesis of approximation errors

, 1977
A method is developed for the synthesis of the error in approximations in the large of regular and irregular functions. The synthesis uses a small class of dimensionless elementary error functions which are weighted by the coefficients of the expansion of the regular part of the function.
Bareiss, E. H., Michel, P.
openaire   +3 more sources

Padé-type approximants and errors of Padé approximants

Journal of Computational and Applied Mathematics, 1998
An estimate of non-local errors of Padé approximation, i.e. not only near the point of expansion in the power series of an approximated function is performed by means of the parallely computed Padé-type approximation, both the approximations being computed with quasi equal orders.
Gilewicz, Jacek, Pindor, Maciej
openaire   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Approximation performance analysis of Oustaloup rational approximation of ideal fractance

工程科学与技术, 2016
:Starting from operational characteristics, in this paper, the operational characteristics localization of zero-pole subsystem of Oustaloup was analyzed based on order-frequency and phase-frequency characteristic function.
Liu Panpan, Yuan Xiao
doaj  

Probabilistic state synthesis based on optimal convex approximation

npj Quantum Information
When preparing a pure state with a quantum circuit, there is an unavoidable approximation error due to the compilation error in fault-tolerant implementation.
Seiseki Akibue, Go Kato, Seiichiro Tani
doaj   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

A Simple But Accurate Approximation for Multivariate Gaussian Rate-Distortion Function and Its Application in Maximal Coding Rate Reduction

Tsinghua Science and Technology
The multivariate Gaussian Rate-Distortion (RD) function is crucial in various applications, such as digital communications, data storage, or neural networks.
Zhenglin Huang, Qifa Yan, Bin Dai, Xiaohu Tang   +3 more
doaj   +1 more source

Quasi-Positive Delta Sequences and Their Applications in Wavelet Approximation

International Journal of Mathematics and Mathematical Sciences, 2016
A sufficient literature is available for the wavelet error of approximation of certain functions in the L2-norm. There is no work in context of multiresolution approximation of a function in the sense of sup-error.
Shyam Lal, Susheel Kumar
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source