Results 111 to 120 of about 10,024,030 (363)
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Approximation properties for dynamical W⁎-correspondences
Advances in Mathematics49 pages.
De Commer, Kenny, De Ro, Joeri Ludo
openaire +3 more sources
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
C?-Property and approximately differentiable functions
Mathematical Notes of the Academy of Sciences of the USSR, 1988 This is a continuation of a previous paper by the same author [Mat. Zametki 44, No. 5, 645-659 (1988; Zbl 0689.26008)]. The main result is the characterization of mappings having \(C^ r\)-property in terms of \(V^ r_ x(f;\rho)\) and \(\text{dist}(0,F\rho(x))\). Recall that a mapping \(f:\mathbb{R}^ n\to\mathbb{R}^ m\) has \(C^ r\) property if for every
openaire +3 more sources
Molecular Oncology, EarlyView.Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source
On How QCD Gauge Invariance Gets Realized in the Context of Effective Locality
Advances in High Energy Physics, 2018 The fermionic Green’s functions of QCD exhibit an unexpected property of effective locality, which appears to be exact, involving no approximation. This property is nonperturbative, resulting from a full integration of the elementary gluonic degrees of ...
H. M. Fried, T. Grandou, R. Hofmann
doaj +1 more source
Runge approximation on convex sets implies the Oka property
, 2005 We prove that the classical Oka property of a complex manifold Y, concerning the existence and homotopy classification of holomorphic mappings from Stein manifolds to Y, is equivalent to a Runge approximation property for holomorphic maps from compact ...
Forstneric, Franc
core
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source