Results 41 to 50 of about 84,532 (265)

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

The tight approximation property

open access: yesJournal für die reine und angewandte Mathematik (Crelles Journal), 2021
AbstractThis article introduces and studies the tight approximation property, a property of algebraic varieties defined over the function field of a complex or real curve that refines the weak approximation property (and the known cohomological obstructions to it) by incorporating an approximation condition in the Euclidean topology.
Benoist, Olivier, Wittenberg, Olivier
openaire   +4 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Disturbance observer-based control with adaptive neural network for unknown nonlinear system

open access: yesMeasurement + Control, 2023
This paper presents an adaptive neural network controller based on a disturbance observer to compensate the disturbance caused by neural network approximation for a class of unknown nonlinear systems.
Jing Hu, Meirong Zheng
doaj   +1 more source

Approximation properties of haplotype tagging

open access: yesBMC Bioinformatics, 2006
AbstractBackgroundSingle nucleotide polymorphisms (SNPs) are locations at which the genomic sequences of population members differ. Since these differences are known to follow patterns, disease association studies are facilitated by identifying SNPs that allow the unique identification of such patterns.
Dreiseitl Stephan   +2 more
openaire   +3 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Fixed points of condensing multivalued maps in topological vector spaces

open access: yesFixed Point Theory and Applications, 2004
With the aid of the simplicial approximation property, we show that every admissible multivalued map from a compact convex subset of a complete metric linear space into itself has a fixed point.
In-Sook Kim
doaj   +2 more sources

The approximation property of some vector valued Sobolev-Slobodeckij spaces

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 1992
In this paper we consider the Sobolev-Slobodeckij spaces Wm,p(ℜn,E) where E is a strict (LF)-space, m∈(0,∞)\ℕ and p∈[1,∞). We prove that Wm,p(ℜn,E) has the approximation property provided E has it, furthermore if E is a Banach space with the strict ...
Carlos Bosch   +2 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

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