Results 81 to 90 of about 84,532 (265)
International Journal of Mathematics and Mathematical Sciences, 2005 A smoothing property in multistep backward difference method for a linear parabolic problem in Hilbert space has been proved, where the operator is selfadjoint, positive definite with compact inverse.
Yubin Yan
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Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
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Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
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Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
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Approximation properties for dynamical W⁎-correspondences
Advances in Mathematics49 pages.
De Commer, Kenny, De Ro, Joeri Ludo
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Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
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C?-Property and approximately differentiable functions
Mathematical Notes of the Academy of Sciences of the USSR, 1988 This is a continuation of a previous paper by the same author [Mat. Zametki 44, No. 5, 645-659 (1988; Zbl 0689.26008)]. The main result is the characterization of mappings having \(C^ r\)-property in terms of \(V^ r_ x(f;\rho)\) and \(\text{dist}(0,F\rho(x))\). Recall that a mapping \(f:\mathbb{R}^ n\to\mathbb{R}^ m\) has \(C^ r\) property if for every
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Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
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On How QCD Gauge Invariance Gets Realized in the Context of Effective Locality
Advances in High Energy Physics, 2018 The fermionic Green’s functions of QCD exhibit an unexpected property of effective locality, which appears to be exact, involving no approximation. This property is nonperturbative, resulting from a full integration of the elementary gluonic degrees of ...
H. M. Fried, T. Grandou, R. Hofmann
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Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
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