Results 131 to 140 of about 189,408 (316)

Social media apps on the Camino de Santiago

open access: yesFrontiers in Communication
IntroductionThe Camino de Santiago continues to beat records in terms of number of pilgrims and increases their popularity internationally, since there are already more foreign than Spanish pilgrims.
José Sixto-García
doaj   +1 more source

Divergent Roles of mGlu2 and mGlu3 Receptors in Amyloid‐β Production and Cognitive Dysfunctions in Alzheimer's Disease

open access: yesAdvanced Science, EarlyView.
This study explores the opposing effects of the mGluR2 and mGluR3 receptors on amyloid precursor protein processing. mGluR2 promotes amyloidogenic cleavage, while mGluR3 favors non‐amyloidogenic pathways. Using a brain‐penetrant nanobody as a mGluR2 positive allosteric modulator, the study uncovers how its chronic activation aggravates amyloid‐β burden
Pierre‐André Lafon   +21 more
wiley   +1 more source

Utilization of Smart APPS Creator (SAC) as Alternative Media for Application-Based Learning: Rubik (Rumah Bahasa Indonesia Kita)

open access: yesJurnal PAJAR (Pendidikan dan Pengajaran)
The purpose of this study was to determine the meaning of application-based learning media during the pandemic and to be able to provide new innovations to the community in creating the RUBIK application as a learning tool, especially Indonesian ...
Nadilah Zahrani
doaj   +1 more source

Lilrb4a Suppression Reprograms Microglia to Mitigate APOE4‐Associated Amyloid Plaques and Cerebral Amyloid Angiopathy in Association With a PPAR‐Linked Pro‐Clearance State

open access: yesAdvanced Science, EarlyView.
Targeting Lilrb4a in Apolipoprotein E4 (APOE4)‐associated Alzheimer's disease (AD) reprograms microglia toward a beneficial, phagocytic state. Genetic deletion or antisense inhibition of Lilrb4a suppresses p‐SHP2/NF‐κB/STAT1 signaling, restores PPAR‐linked lipid and energy metabolism, and reduces amyloid plaque burden and cerebral amyloid angiopathy ...
Changxu Nie   +12 more
wiley   +1 more source

Variable disease resistance to Sclerotinia sclerotiorum in traditional New Zealand/Māori sweet potato cultivars

open access: yes, 2013
Sweet potato (Ipomea batatas (L.) Lam.) or kumara, is a crop of cultural significance brought to New Zealand by Maori nearly 1000 years ago. Current commercial production in New Zealand is based on three cultivars ‘Beauregard’, ‘Owairaka red’ and ...
Fuller, R
core  

Health apps and knowledge translation

open access: yes, 2018
It is undeniable that technology is changing the landscape of health care with unprecedented access to information for consumers and an upsurge in availability of health and wellness applications (apps).
Gustafsson, Louise, Louise Gustafsson
core   +1 more source

Toward Prostate Cancer Early Warning with a Self‐Powered Wearable Biosensing Platform Integrated with Machine Learning

open access: yesAdvanced Science, EarlyView.
ABSTRACT Current prostate cancer detection methods remain limited in non‐invasiveness and specificity, prompting interest in urinary biomarkers such as sarcosine. Here, we report a urine‐powered wearable platform for non‐invasive sarcosine detection as a proof‐of‐concept for decentralized early warning.
Jing Xu   +10 more
wiley   +1 more source

gCube PerformFISH-Apps Portlet

open access: yes, 2019
PerformFISH Apps is a set of portlet for the implementation of the Form Submission useful to calculate KPIs Support Bugs and support requests can be reported in the gCube issue tracking tool: https://support.d4science.org/projects/gcube/ ──────────
Massimiliano Assante (5203816)   +1 more
core   +1 more source

Fine‐Tuned Regulation of mRNA Translation and Transport by STAU2 Condensate Facilitates Neuronal Development and Plasticity

open access: yesAdvanced Science, EarlyView.
STAU2 undergoes phase separation to form dynamic condensates that package target mRNAs and deliver them to the distal ends of growing neuronal dendrites. STAU2 condensates stabilize embedded mRNAs and repress their translation. Synaptic activity bidirectionally remodels STAU2 condensates, coordinating local translation of STAU2‐associated mRNAs ...
Shijing Huang   +8 more
wiley   +1 more source

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