Results 31 to 40 of about 355,235 (293)

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta   +6 more
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Screening of bread wheat genotypes for identification of novel stripe rust resistance genes using molecular markers

open access: yesElectronic Journal of Plant Breeding
Stripe Rust, caused by Puccinia striiformis Westend f. sp. tritici , is an important fungal disease of wheat worldwide. In this study, 41 wheat genotypes from various institutes across India were screened for adult plant resistance (APR) in field trials,
Rubby Sandhu1,2*, Bikram Singh1, Amardeep Kour1, I.R. Delvadiya2 and Shweta Sharma2
doaj   +1 more source

sj-pdf-1-apr-10.1177_1532673X211046252 – Supplemental material for Gubernatorial Elections Change Demand for Local Newspapers

open access: yes, 2021
Supplemental material, sj-pdf-1-apr-10.1177_1532673X211046252 for Gubernatorial Elections Change Demand for Local Newspapers by Allison M. N. Archer and Joshua P.
Allison M. N. Archer (11468520)   +1 more
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Realization of foreign-policy strategy of the United States of America is in countries of south-east Asia

open access: yesАмериканська історія і політика, 2016
The article attempts to analyze and consider implementation of foreign policy strategy of America on the Association of Southeast Asian Nations; highlights the geopolitical relations of the USA and ASEAN.
Inna Podbereznykh
doaj   +1 more source

sj-pdf-1-apr-10.1177_1532673X211041570 – Supplemental material for Reliable Sources? Correcting Misinformation in Polarized Media Environments

open access: yes, 2021
Supplemental material, sj-pdf-1-apr-10.1177_1532673X211041570 for Reliable Sources? Correcting Misinformation in Polarized Media Environments by Patrick W. Kraft, Nicholas R. Davis, Taraleigh Davis, Amanda Heideman, Jason T.
Taraleigh Davis (11403941)   +5 more
core   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

sj-pdf-1-apr-10.1177_1532673X211042001 – Supplemental material for Reexamining the Effects of Electoral Competition on Negative Advertising

open access: yes, 2021
Supplemental material, sj-pdf-1-apr-10.1177_1532673X211042001 for Reexamining the Effects of Electoral Competition on Negative Advertising by Kevin K.
Kevin K. Banda (5024909)
core   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

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