Results 31 to 40 of about 42,389 (194)

The simulation of action disorganisation in complex activities of daily living [PDF]

, 2005
Action selection in everyday goal-directed tasks of moderate complexity is known to be subject to breakdown following extensive frontal brain injury. A model of action selection in such tasks is presented and used to explore three hypotheses concerning ...
Anderson JR, Cooper RP, Cooper RP, Duncan J, Fuster JM, Grafman J, Houghton G, Houghton G, Humphreys GW, Humphreys GW, Liepmann H, Luria AR, McClelland JL, Myrna F. Schwartz, Norman DA, Norman DA, Passingham RE, Peter Yule, Pick A, Poeck K, Reason JT, Reason JT, Richard P. Cooper, Rumiati RI, Schwartz MF, Shallice T, Sirigu A, Tim Shallice, Verfaellie M, Williams RJ, Yule P, Zipf GK   +31 more
core   +1 more source

DNA strand break repair and neurodegeneration. [PDF]

, 2013
A number of DNA repair disorders are known to cause neurological problems. These disorders can be broadly characterised into early developmental, mid-to-late developmental or progressive.
Abraham, Ahel, Alano, Alderton, Alter, Barbi, Barlow, Barnes, Bayatti, Bendixen, Bohr, Bootsma, Breslin, Brown, Buck, Buis, Caldecott, Caldecott, Caldecott, Cantoni, Chappell, Clements, Cortes Ledesma, Date, de Boer, de Boer, de Klein, de Vries, Delaval, Derheimer, Donahue, Durocher, El-Khamisy, El-Khamisy, El-Khamisy, Eliasson, Fattah, Frank, Frank, Frappart, Gao, Gao, Gatz, Goodship, Griffith, Gruber, Gueven, Henning, Hoeijmakers, Hoeijmakers, Jackson, Jeggo, Jilani, Kathe, Katyal, Keith W. Caldecott, Koch, Kuzminov, Lakin, Lakshmipathy, LaMonica, Le Ber, Lee, Lee, Lee, Lehmann, Letinic, Li, Licht, Lieber, Lindahl, Ljungman, Ljungman, Loizou, Luo, Mallery, Mao, Matsuura, Mayne, McKinnon, McKinnon, Mellon, Mischo, Mitchell, Moreira, Moreira, Moreno-Herrero, Morris, Moynahan, Mu, Murai, Murai, Murga, Nakane, Nance, Nilsen, Nussenzweig, Ogi, Okano, Orii, Osterod, Ouyang, O’Driscoll, O’Driscoll, O’Driscoll, Paula-Barbosa, Paull, Puebla-Osorio, Resnick, Revet, Reynolds, Reynolds, Rouse, Sanai, Schumacher, Shechter, Shen, Shiloh, Shull, Sidman, Skourti-Stathaki, Sleeth, Sonoda, Stefanini, Stewart, Stiff, Stuart L. Rulten, Sugasawa, Syljuasen, Takashima, Taylor, Tebbs, Theunissen, Thorslund, Uziel, van der Burg, van der Horst, Varon, Verhagen, Vinters, Virag, Vrouwe, Waltes, Weeda, Weterings, Whitehouse, Williams, Williams, Xu, Yu, Yu, Yuce, Zecevic, Zecevic, Zhou, Zhou, Zhu, Zou   +157 more
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Reviewing the limb apraxia concept: From definition to cognitive neuropsychological models

Dementia & Neuropsychologia
Apraxia is a disorder of learned skilled movements, in the absence of elementary motor or sensory deficits and general cognitive impairment such as inattention to commands, object-recognition deficits or poor oral comprehension.
Joana Mantovani-Nagaoka, Karin Zazo Ortiz   +1 more
doaj   +1 more source

Limb apraxia in multiple sclerosis [PDF]

Vojnosanitetski Pregled, 2014
Background/Aim. There are almost no studies on apraxia in people with multiple sclerosis. Although the white matter is damaged in MS, it is not the only location in which the pathological changes are present.
Rapaić Dragan, Medenica Veselin, Kozomora Ružica, Ivanović Lidija   +3 more
doaj   +1 more source

Expression of a pathogenic mutation of SOD1 sensitizes aprataxin-deficient cells and mice to oxidative stress and triggers hallmarks of premature ageing [PDF]

, 2014
Aprataxin (APTX) deficiency causes progressive cerebellar degeneration, ataxia and oculomotor apraxia in man. Cell free assays and crystal structure studies demonstrate a role for APTX in resolving 5'-adenylated nucleic acid breaks, however, APTX ...
Bode, David, Carroll, Jean, Chiang, Shih-Chieh, El-Khamisy, Sherif F, Greensmith, Linda, Hafezparast, Majid, Kalmar, Bernadett, Mckinnon, Peter J, Page, Tristan K W, Thorpe, Julian R   +9 more
core   +1 more source

Limb apraxia and the 'affordance competition hypothesis'

Frontiers in Human Neuroscience, 2015
Limb apraxia, a disorder of higher order motor control, has long been a challenge for clinical assessment and understanding (Leiguarda and Marsden 2000).The deficits originally described in limb apraxia (Liepmann 1908) have been classified by the nature ...
Elisabeth eRounis, Glyn eHumphreys
doaj   +1 more source

Ataxia in children: early recognition and clinical evaluation [PDF]

, 2017
Background: Ataxia is a sign of different disorders involving any level of the nervous system and consisting of impaired coordination of movement and balance.
Falsaperla, Raffaele, Lubrano, Riccardo, Pavone, Piero, Pavone, Vito, Praticò, Andrea D., Rizzo, Renata, Ruggieri, Martino   +6 more
core   +1 more source

Upper and Lower Face and Ideomotor Apraxia in Patients with Alzheimer’s Disease

Behavioural Neurology, 2003
Introduction: Apraxia of face movement in Alzheimer's disease (AD) has been rarely investigated. This study aimed at investigating the frequency of lower (mouth, tongue and throat) and upper (eyes and eyebrows) face apraxia, in AD and its relationship ...
Jay Guido Capone, Sergio Della Sala, Hans Spinnler, Annalena Venneri   +3 more
doaj   +1 more source

Apraxia in progressive nonfluent aphasia [PDF]

, 2010
The clinical and neuroanatomical correlates of specific apraxias in neurodegenerative disease are not well understood. Here we addressed this issue in progressive nonfluent aphasia (PNFA), a canonical subtype of frontotemporal lobar degeneration that has
Rohrer, J.D., Rossor, M.N., Warren, J.D.
core  

Non-speech oro-motor exercise use in acquired dysarthria management : regimes and rationales [PDF]

, 2011
Non-speech oro-motor exercises (NSOMExs) are described in speech and language therapy (SLT) manuals, and are thought to be much used in acquired dysarthria intervention, though there is no robust evidence of an influence on speech outcome.
Allen, Carolyn, Mackenzie, Catherine, Muir, Margaret   +2 more
core   +1 more source