Results 61 to 70 of about 284 (126)

Review on: Aprocitentan Unveiled: A New Horizon in Anti-Hypertensive Therapy

Aprocitentan is an oral once-daily dual endothelin-1 receptor antagonist preventing ET-1 binding quite effectively to ETA and ETB receptors.It is a derivative of macitentan somewhat oddly used in treating pulmonary arterial hypertension with orphan drug status. Aprocitentan gets eliminated slowly in urine and faeces after being highly bound to proteins.
openaire   +1 more source

2025 Update on resistant hypertension in CKD: where do we stand and where do we go? [PDF]

Clin Kidney J
Schmieder RE.
europepmc   +1 more source

The dual endothelin-1 antagonist aprocitentan alleviates mitochondrial oxidative stress in human cardiac fibroblasts. [PDF]

Eur Heart J Cardiovasc Pharmacother
Varzideh F, Jankauskas SS, Jain U, Soderquist L, Densu Agyapong E, Kansakar U, Santulli G.   +6 more
europepmc   +1 more source

Management of hypertension in chronic kidney disease: current perspectives and therapeutic strategies. [PDF]

Front Med (Lausanne)
Alsalloum MA, Albekery MA, Alhomoud IS.
europepmc   +1 more source

Emerging therapeutic frontiers in hypertension management. [PDF]

Front Cardiovasc Med
Pena DL, Aurelian J, Grigore M, Hodorogea AS, Weiss E, Bădilă E, Ilieșiu AM, Balahura AM.   +7 more
europepmc   +1 more source

Recent developments in the management of resistant hypertension: focus on endothelin receptor antagonists. [PDF]

Future Cardiol
Heidari Nejad S, Azzam O, Schlaich MP.
europepmc   +1 more source

Resistant hypertension: Epidemiology, mechanisms and contemporary therapeutic strategies. [PDF]

Heart Int
Sharma R, Varma R, Siwach A, Nagal A, Sehgal P, Sharma M, Shah B, Ray I, Kunal S.   +8 more
europepmc   +1 more source

The Journey of Resistant Hypertension: From the Fifth Report of the Joint National Committee on Detection, Evaluation, and Treatment of High Blood Pressure to American Heart Association/American College of Cardiology Guidelines. [PDF]

Circulation
Vongpatanasin W, Turcu AF.
europepmc   +1 more source

Management of hypertension in chronic kidney disease. [PDF]

Clin Med (Lond)
Doulton T, Swift PA, Hiremath S.
europepmc   +1 more source

Correction to: The dual endothelin-1 antagonist aprocitentan alleviates mitochondrial oxidative stress in human cardiac fibroblasts. [PDF]

Eur Heart J Cardiovasc Pharmacother
europepmc   +1 more source