Results 271 to 280 of about 114,443 (322)
Protamine cleavage specificity of the avian pathogen Escherichia coli OmpT reveals two substrate-binding sites related to virulence. [PDF]
Liu J+6 more
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New methods for improving pancreas preservation. [PDF]
Elzawahry MA, Reichman T, Sutherland A.
europepmc +1 more source
AntifibrinolyticAgents: Aprotinin, and Desmopressin
Pramila Bajaj
doaj
Protocol for reconstituting enzymatic activities for ultra-large histone methyltransferases NSD1 and SETD2 using a baculovirus expression system. [PDF]
Hsu CI, Yeh E, Chen CCL, Sahn M, Yu JR.
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Annals of Pharmacotherapy, 1996
OBJECTIVE: To review the clinical pharmacology of aprotinin in patients undergoing surgical procedures involving major blood loss, namely, coronary artery bypass graft (CABG). DATA SOURCES: A MEDLINE search was used to identify French-and English-language publications on aprotinin using the indexing terms aprotinin, cardiothoracic surgery, and ...
S, Robert+3 more
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OBJECTIVE: To review the clinical pharmacology of aprotinin in patients undergoing surgical procedures involving major blood loss, namely, coronary artery bypass graft (CABG). DATA SOURCES: A MEDLINE search was used to identify French-and English-language publications on aprotinin using the indexing terms aprotinin, cardiothoracic surgery, and ...
S, Robert+3 more
openaire +2 more sources
Aprotinin: is it prothrombotic?
Perfusion, 2001Controversy continues as to whether aprotinin (Trasylol) is prothrombotic. The recent discovery of the thrombin receptor family, known as the protease-activated receptor family (PAR) has been essential in aiding our understanding of the mechanism of action of aprotinin.
Michael Poullis+2 more
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Aprotinin for intraoperative haemostasis
Neurosurgical Review, 1981Because of the special anatomical conditions of neurosurgery, the success of any operation depends on accurate haemostasis. This paper reports on an additional measure for the achievement of intraoperative haemostasis which has been successfully used during more than 1200 neurosurgical interventions. Meninges and cerebral tissue contain relatively high
D. Giromini, T. Tzonos
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Expression, purification and characterization of aprotinin and a human analogue of aprotinin
Protein Expression and Purification, 2009Aprotinin is a Kunitz-type inhibitor with a relatively broad specificity. It has been shown to be clinically useful for the management of hemorrhagic complications. In this report, small ubiquitin-related modifier (SUMO) linked with a hexa-histidine tag was used as a fusion partner for the production of recombinant aprotinin and a human aprotinin ...
Fengyuan Tang+6 more
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Aprotinin and renal dysfunction
Expert Opinion on Drug Safety, 2008Aprotinin is a polypeptide serine protease inhibitor used to prevent bleeding and need for transfusions in patients having heart surgery. A recent analysis of an observational study data set suggested the use of aprotinin was associated with an increased risk of developing renal failure.
David Royston, Marie Bosman
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