Results 1 to 10 of about 455,903 (227)

Preexisting autoantibodies to type I IFNs underlie critical COVID-19 pneumonia in patients with APS-1

Journal of Experimental Medicine, 2021
Patients with autoimmune polyendocrine syndrome type-1 (APS-1) have circulating auto-Abs neutralizing most type I interferons. These auto-Abs can underlie life-threatening COVID-19 pneumonia in the general population. The authors report 22 APS-1 patients
Paul Bastard, E. Orlova, L. Sozaeva, R. Lévy, A. James, Monica M. Schmitt, S. Ochoa, M. Kareva, Yulia Rodina, A. Gervais, Tom Le Voyer, J. Rosain, Q. Philippot, Anna-Lena Neehus, E. Shaw, M. Migaud, Lucy Bizien, O. Ekwall, S. Berg, G. Beccuti, L. Ghizzoni, G. Thiriez, A. Pavot, C. Goujard, M. Frémond, Edwin Carter, A. Rothenbuhler, A. Linglart, Brigite Mignot, A. Comte, N. Cheikh, O. Hermine, L. Breivik, E. Husebye, S. Humbert, P. Rohrlich, A. Coaquette, Fanny Vuoto, K. Faure, N. Mahlaoui, P. Kotnik, T. Battelino, K. Trebušak Podkrajšek, K. Kisand, Elise M. N. Ferré, T. DiMaggio, Lindsey B. Rosen, P. Burbelo, Martin McIntyre, Nelli Y. Kann, A. Shcherbina, M. Pavlova, A. Kolodkina, S. Holland, Shen-Ying Zhang, Y. Crow, L. Notarangelo, H. Su, L. Abel, Mark S. Anderson, E. Jouanguy, B. Neven, A. Puel, J. Casanova, M. Lionakis   +64 more
semanticscholar   +1 more source

Lactobacillus acidophilus (LA) Fermenting Astragalus Polysaccharides (APS) Improves Calcium Absorption and Osteoporosis by Altering Gut Microbiota

Foods, 2023
Lactobacillus acidophilus (LA) and Astragalus polysaccharides (APS) have each been shown to have anti-osteoporotic activity, and the aim of this study was to further investigate whether the LA fermenting APS was more effective in improving calcium ...
Junhua Zhou, Jing Cheng, Liu Liu, Jianming Luo, Xichun Peng   +4 more
semanticscholar   +1 more source

How do apes ape? [PDF]

Learning & Behavior, 2004
In the wake of telling critiques of the foundations on which earlier conclusions were based, the last 15 years have witnessed a renaissance in the study of social learning in apes. As a result, we are able to review 31 experimental studies from this period in which social learning in chimpanzees, gorillas, and orangutans has been investigated.
A. Whiten, V. Horner V, C. Litchfield, S. Marshall-Pescini   +3 more
openaire   +3 more sources

Building an SDN Enterprise WLAN Based on Virtual APs [PDF]

IEEE Communications Letters, 2020
In this letter, the development and testing of an open enterprise Wi-Fi solution based on virtual access points (APs), managed by a central WLAN controller is presented.
Luis Sequeira, Juan Luis Ignacio de la Cruz, J. Ruiz-Mas, J. Saldaña, J. Fernández-Navajas, J. Almodóvar   +5 more
semanticscholar   +1 more source

Astragalus polysaccharide (APS) attenuated PD-L1-mediated immunosuppression via the miR-133a-3p/MSN axis in HCC

Pharmaceutical Biology, 2022
Context Astragalus polysaccharide (APS) is a new tumour therapeutic drug, that has an inhibitory effect on a variety of solid tumours. Tumour cell immunosuppression is related to the up-regulation of programmed death ligand 1 (PD-L1).
Lihua He, Kecheng Xu, Lizhi Niu, Lizhu Lin   +3 more
semanticscholar   +1 more source

Mild COVID-19 despite autoantibodies to type I IFNs in Autoimmune-Polyendocrine-Syndrome Type 1 (APS-1).

Journal of Clinical Investigation, 2021
Autoantibodies to interferon(IFN)-α and IFN-ω (type I IFNs) were recently reported as causative for severe COVID-19 in the general population. Autoantibodies against IFN-α and IFN-ω are present in almost all patients with Autoimmune-Polyendocrine ...
C. Meisel, Bengisu Akbil, Tim Meyer, E. Lankes, V. Corman, O. Staudacher, N. Unterwalder, U. Kölsch, C. Drosten, M. Mall, T. Kallinich, D. Schnabel, C. Goffinet, Horst von Bernuth   +13 more
semanticscholar   +1 more source

Avaliação, Monitoramento e Melhoria da Qualidade na APS

APS EM REVISTA, 2021
Esta nota técnica se insere no conjunto de ações desenvolvidas pela Rede de Pesquisa em Atenção Primária à Saúde e apresenta sua posição sobre avaliação, monitoramento e melhoria da qualidade na APS. Em um contexto de grave crise sanitária que desnuda as
Elaine Tomasi, F. Nedel, Allan Claudius Queiroz Barbosa   +2 more
semanticscholar   +1 more source

Optimizing the integration of advanced practitioners in a department of surgery: An operational improvement model [PDF]

, 2018
Physician assistants (PAs) and nurse practitioners (NPs) have established themselves as key members of the healthcare team to supplement practicing physicians in patient care.
Dunnington, Gary, Hockaday, Melissa, Smith, Cecelia, Torbeck, Laura J.   +3 more
core   +1 more source

Selective AP-sequence Based Indoor Localization without Site Survey [PDF]

, 2016
In this paper, we propose an indoor localization system employing ordered sequence of access points (APs) based on received signal strength (RSS). Unlike existing indoor localization systems, our approach does not require any time-consuming and laborious
Guo, Jindong, Liu, Ran, Liu, Xiang, Mo, Ronghong, Pamadi, Vishesh N, Yuen, Chau, Zhao, Jun   +6 more
core   +1 more source

Multidimensional measurement within adult protective services: design and initial testing of the tool for risk, interventions, and outcomes. [PDF]

, 2014
This study describes the development, field utility, reliability, and validity of the multidimensional Tool for Risk, Interventions, and Outcomes (TRIO) for use in Adult Protective Services (APS).
Aarons, Gregory A, Henderson, Linda B, Snider, Marcy A, Sommerfeld, David H   +3 more
core   +2 more sources