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AP sites and AP endonucleases

Biochimie, 1982
The sensitivity of internal and terminal apurinic/apyrimidinic (AP) sites to alkaline hydrolysis and beta-elimination is described. The symmetric and asymmetric modes of endonucleolytic hydrolysis by specific AP endonucleases are compared and the discrimination between their non-enzymatic and catalytic mechanism is discussed.
L, Grossman, R, Grafstrom
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Renal Involvement in the Antiphospholipid Syndrome (APS)—APS Nephropathy

open access: yesClinical Reviews in Allergy and Immunology, 2008
Although the kidney represents a major target organ in antiphospholipid syndrome (APS), renal involvement in APS was poorly recognized until recently. The most well-recognized renal manifestations of APS are the renal artery thrombosis/stenosis, renal infarction, hypertension, renal vein thrombosis, end-stage renal disease, increased allograft vascular
Maria G Tektonidou, Tektonidou Maria G
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Apes ape!

Behavioral and Brain Sciences, 1998
Heyes's claim that the only unequivocal evidence of motor imitation comes from rats and budgerigars is contested. It is suggested that the rats' behavior can be explained by emulation and the budgerigars' by response facilitation. Behavioral matching in chimpanzees (Custance et al. 1995; Whiten et al. 1996) is reconsidered and interpreted in terms
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APS and the brain

Lupus, 2003
Antiphospholipid antibody syndrome (APS) may present with neurological syndromes. Cerebrovascular disease, chorea/ballismus, epileptic seizures, headache, cognitive impairment, transverse myelopathy, Devic’s syndrome and multiple sclerosis-like presentations feature among others.
J, Sastre-Garriga, X, Montalban
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Genome of the apes

Trends in Genetics, 2001
The Human Genome Project has generated both the information and technological infrastructure needed to accelerate genetic comparisons between humans and the African great apes (chimpanzees and gorillas). Sequence and chromosomal organization differences between these highly related genomes will provide clues to the genetic basis for recently evolved ...
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Ethnicity and APS

Journal of Autoimmunity, 2000
Ethnic and geographic studies have contributed to knowledge of the clinical epidemiology of APS. In general, these studies support the associations of aPL with thrombosis and pregnancy morbidity, with some exceptions. Further investigation is needed to determine whether the exceptions represent interethnic variation in the clinical associations of aPL ...
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