The Anti-Inflammatory Effect of Aptamin C on House Dust Mite Extract-Induced Inflammation in Keratinocytes via Regulation of IL-22 and GDNF Production [PDF]
Antioxidants, 2021 Atopic dermatitis (AD), a chronic inflammatory skin disease, is characterized by eczemous lesions on the skin that manifest as severe itching and last a long time.
Go Cheol Hyeon +2 more
exaly +8 more sources
Anti-Inflammatory Effects of Aptamin C in Pulmonary Fibrosis Induced by Bleomycin [PDF]
PharmaceuticalsBackground/Objectives: Vitamin C is a well-known antioxidant with antiviral, anticancer, and anti-inflammatory properties. However, its therapeutic applications are limited by rapid oxidation due to heat and light sensitivity.
Jae Seung Kang, Yejin Kim, Seoyoun Jeong
exaly +7 more sources
Effect of Aptamin C on NK Cell Activity and Cytotoxicity: A Randomized Placebo-Controlled Trial and In Vitro Comparison with Vitamin C. [PDF]
AntioxidantsNatural killer (NK) cells are crucial components of innate immunity and rapidly eliminate abnormal cells through ligand–receptor signaling without prior sensitization.
Jae Seung Kang, Yejin Kim, Jeong-Ho Park
exaly +6 more sources
NXP032 Ameliorates Aging-Induced Oxidative Stress and Cognitive Impairment in Mice through Activation of Nrf2 Signaling [PDF]
Antioxidants, 2022 Aging is a neurodegenerative disease that leads to cognitive impairment, and an increase in oxidative stress as a major cause is an important factor.
Joo Hee Lee, Min Kyung Song, Jae Min Lee
exaly +5 more sources
NXP031 prevents dopaminergic neuronal loss and oxidative damage in the AAV-WT-α-synuclein mouse model of Parkinson’s disease [PDF]
PLoS ONE, 2022 Parkinson's disease (PD) is a neurodegenerative disease characterized by inclusions of aggregated α-synuclein (α-Syn). Oxidative stress plays a critical role in nigrostriatal degeneration and is responsible for α-Syn aggregation in PD.
Yoon-Seong Kim, Min Kyung Song
exaly +3 more sources
Advances in dermatology using DNA aptamer “Aptamin C” innovation: Oxidative stress prevention and effect maximization of vitamin C through antioxidation [PDF]
Journal of Cosmetic Dermatology, 2020 AbstractBackgroundVitamin C (also known as L‐ascorbic acid) plays a critical role in reactive oxygen species (ROS) reduction and cell regeneration by protecting cell from oxidative stress. Although vitamin C is widely used in cosmetic and therapeutic markets, there is considerable evidence that vitamin C easily undergoes oxidation by air, pH ...
Moon-Young Yoon +2 more
exaly +6 more sources
Aptamin C enhances anti-cancer activity NK cells through the activation of STAT3: a comparative study with vitamin C [PDF]
Anatomy and Cell BiologyVitamin C is a well-known antioxidant with antiviral, anticancer, and anti-inflammatory properties based on its antioxidative function. Aptamin C, a complex of vitamin C with its specific aptamer, has been reported to maintain or even enhance the efficacy of vitamin C while increasing its stability.
Jae Seung Kang, Yejin Kim
exaly +4 more sources
Participation of c-FLIP in NLRP3 and AIM2 inflammasome activation
, 2017 Cellular FLICE-inhibitory protein (c-FLIP) is an inhibitor of caspase-8 and is required for macrophage survival. Recent studies have revealed a selective role of caspase-8 in noncanonical IL-1 beta production that is independent of caspase-1 or ...
賴明宗 +1 more
core +1 more source
, 2023 Hepatitis C is a virus that causes Hepatitis. There are 4 different types of Viral Hepatitis A,B,C,D and E. Hepatitis C is an infection of th liver caused by the Hepatitis C Virus. The virus gets into your body through infected blood.
core
Surface melt and runoff on Antarctic ice shelves at 1.5°C, 2°C and 4°C of future warming [PDF]
, 2021 The future surface mass balance (SMB) of Antarctic ice shelves has not been constrained with models of sufficient resolution and complexity. Here, we force the high‐resolution Modèle Atmosphérique Régional (MAR) with future simulations from four CMIP ...
Gilbert, Ella +5 more
core +1 more source