Results 21 to 30 of about 64,606 (299)

Aquaporin-2 Inhibitors [PDF]

Journal of the American Society of Nephrology, 2013
The critical contribution of aquaporin-2 (AQP) to water homeostasis in mammals is highlighted by the severe concentrating defects seen in humans with mutations in the AQP2 gene and in mice that are AQP2 null or have loss-of-function mutations in AQP2 .[1][1],[2][2] The role of the ...
Dennis, Brown, Hua A Jenny, Lu
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Aquaporin-2 in the “-omics” Era [PDF]

Journal of Biological Chemistry, 2009
Vasopressin controls renal water excretion largely through actions to regulate the water channel aquaporin-2 in collecting duct principal cells. Our knowledge of the mechanisms involved has increased markedly in recent years with the advent of methods for large-scale systems-level profiling such as protein mass spectrometry, yeast two-hybrid analysis ...
Jason D, Hoffert, Chung-Lin, Chou, Mark A, Knepper   +2 more
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Aquaporin-10 represents an alternative pathway for glycerol efflux from human adipocytes. [PDF]

PLoS ONE, 2013
BACKGROUND: Glycerol outflow from adipocytes has been considered for a decade to be mediated by aquaporin-7, an aquaglyceroporin highly expressed in the adipose tissue. Its involvement in glycerol metabolism has been widely studied also in humans. Recent
Umberto Laforenza, Manuela F Scaffino, Giulia Gastaldi   +2 more
doaj   +1 more source

Barley plasma membrane intrinsic proteins (PIP aquaporins) as water and CO2 transporters [PDF]

, 2008
We identified barley aquaporins and demonstrated that one, HvPIP2;1, transports water and CO2. Regarding water homeostasis in plants, regulations of aquaporin expression were observed in many plants under several environmental stresses. Under salt stress,
C Zhu, DT Clarkson, DT Luu, E Zelazny, F Chaumont, GJ Cooper, GP Bienert, I Terashima, J Flexas, J Sakurai, J Takano, JF Ma, JY Jang, K Fetter, K Sato-Nara, LH Liu, M Katsuhara, M Katsuhara, M Katsuhara, M Katsuhara, Maki Katsuhara, N Uehlein, NL Nakhoul, P Kjellbom, R Aharon, R Vandeleur, S Suga, S Törnroth-Horsefield, SD Tyerman, TP Jahn, U Johanson, X Yang, YT Hanba, Yuko T. Hanba   +33 more
core   +1 more source

Expression and prognostic value of aquaporin 1, 3 in cervical carcinoma in women of Uygur ethnicity from Xinjiang, China. [PDF]

PLoS ONE, 2014
BACKGROUND: Overexpression of several aquaporins has been reported in different types of human cancer but the role of aquaporins in carcinogenesis has not yet been clearly defined.
Rui Chen, Yonghua Shi, Reshalaity Amiduo, Talaf Tuokan, Lalai Suzuk   +4 more
doaj   +1 more source

Expression and Localization of aquaporin‐1 in Temporomandibular Joint Disc with Internal Derangement [PDF]

, 2012
Background: Internal derangement is the most frequent arthropathy affecting the temporomandibular joint, where its commonest form is anterior disc displacement with or without reduction.
Almeida, Luis Eduardo, Caltabiano, Rosario, Carnazza, Maria Luisa, Galanti, Concetta, Leonardi, Rosalia, Loreto, Carla, Musumeci, Giuseppe, Pannone, Giuseppe   +7 more
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Aquaporin-2 membrane targeting: still a conundrum [PDF]

American Journal of Physiology-Renal Physiology, 2017
The targeting of the water channel aquaporin-2 (AQP2) to the apical plasma membrane of kidney collecting duct principal cells is regulated mainly by the antidiuretic peptide hormone arginine vasopressin (AVP). This process is of crucial importance for the maintenance of body water homeostasis.
Olesen, Emma Tina Bisgaard, Fenton, Robert A.   +1 more
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Vascular Inflammation Is Associated with Loss of Aquaporin 1 Expression on Endothelial Cells and Increased Fluid Leakage in SARS-CoV-2 Infected Golden Syrian Hamsters

Viruses, 2021
Vascular changes represent a characteristic feature of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection leading to a breakdown of the vascular barrier and subsequent edema formation.
Lisa Allnoch, Georg Beythien, Eva Leitzen, Kathrin Becker, Franz-Josef Kaup, Stephanie Stanelle-Bertram, Berfin Schaumburg, Nancy Mounogou Kouassi, Sebastian Beck, Martin Zickler, Vanessa Herder, Gülsah Gabriel, Wolfgang Baumgärtner   +12 more
doaj   +1 more source

Aquaporin-4 and brain edema. [PDF]

, 2007
Aquaporin-4 (AQP4) is a water-channel protein expressed strongly in the brain, predominantly in astrocyte foot processes at the borders between the brain parenchyma and major fluid compartments, including cerebrospinal fluid (CSF) and blood.
A Lehmenkuhler, Alan S. Verkman, AS Verkman, AS Verkman, D Wenzel, DK Binder, DK Binder, DK Binder, DS Prough, GT Manley, H Wen, HJ Reulen, HK Kimelberg, I Klatzo, I Roberts, J Badaut, J Hu, J Li, J Li, JE Rash, JE Rash, K Oshio, KI Auguste, M Amiry-Moghaddam, M Amiry-Moghaddam, M Elkjaer, Marios C. Papadopoulos, MC Papadopoulos, MC Papadopoulos, MC Papadopoulos, NR Saunders, O Bloch, P Agre, P Padmawar, PM Rodier, S Nielsen, S Saadoun, S Saadoun, T Ma   +38 more
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Aquaporin‐2 regulation in health and disease [PDF]

Veterinary Clinical Pathology, 2012
AbstractAquaporin‐2 (AQP2), the vasopressin‐regulated water channel of the renal collecting duct, is dysregulated in numerous disorders of water balance in people and animals, including those associated with polyuria (urinary tract obstruction, hypokalemia, inflammation, and lithium toxicity) and with dilutional hyponatremia (syndrome of inappropriate ...
Radin, M J, Yu, Ming-Jiun, Stødkilde-Jørgensen, Lene, Miller, R L, Hoffert, Jason D., Frøkiær, Jørgen, Pisitkun, Trairak, Knepper, Mark   +7 more
openaire   +3 more sources