Results 21 to 30 of about 22,200,369 (327)
Minireview: Aquaporin 2 Trafficking [PDF]
Endocrinology, 2005 In the kidney aquaporin-2 (AQP2) provides a target for hormonal regulation of water transport by vasopressin. Short-term control of water permeability occurs via vesicular trafficking of AQP2 and long-term control through changes in the abundance of AQP2 and AQP3 water channels.
VALENTI, Giovanna +4 more
openaire +3 more sources
'Aquaporin-omics': mechanisms of aquaporin-2 loss in polyuric disorders. [PDF]
J Physiol, 2023 AbstractAnimal models of a variety of acquired nephrogenic diabetes insipidus (NDI) disorders have identified a common feature: all such models are associated with the loss of aquaporin‐2 (AQP2) from collecting duct principal cells, explaining the associated polyuria.
Mak A +4 more
europepmc +3 more sources
Frontiers in Cardiovascular Medicine, 2022 In addition to long-term regulation of blood pressure (BP), in the kidney resides the initial trigger for hypertension development due to an altered capacity to excrete sodium and water.
Ignazio Verzicco +17 more
doaj +1 more source
A Micropeptide MIAC Inhibits HNSCC Progression by Interacting with Aquaporin 2.
Journal of the American Chemical Society, 2020 Several important micropeptides encoded by noncoding RNAs have been identified in recent years, however, there has never been any reports of micropeptide in head and neck squamous cell carcinoma (HNSCC).
Mengwei Li +12 more
semanticscholar +1 more source
Effect of Diet and Water Intake on Aquaporin 2 Function [PDF]
Childhood Kidney Diseases, 2016 Appropriate control of diet and water intake is important for maintaining normal blood pressure, fluid and electrolyte homeostasis in the body. It is relatively understood that the amount of sodium and potassium intake directly affects blood pressure and
Jun-Mo Kim, Tae-Hee Kim, Tong Wang
doaj +1 more source
Journal of the American Society of Nephrology, 2013 The critical contribution of aquaporin-2 (AQP) to water homeostasis in mammals is highlighted by the severe concentrating defects seen in humans with mutations in the AQP2 gene and in mice that are AQP2 null or have loss-of-function mutations in AQP2 .[1][1],[2][2] The role of the ...
Dennis, Brown, Hua A Jenny, Lu
openaire +2 more sources
Aquaporin‐2 regulation in health and disease [PDF]
Veterinary Clinical Pathology, 2012 AbstractAquaporin‐2 (AQP2), the vasopressin‐regulated water channel of the renal collecting duct, is dysregulated in numerous disorders of water balance in people and animals, including those associated with polyuria (urinary tract obstruction, hypokalemia, inflammation, and lithium toxicity) and with dilutional hyponatremia (syndrome of inappropriate ...
M. Judith Radin +7 more
openalex +5 more sources
Aquaporin-2 in the “-omics” Era [PDF]
Journal of Biological Chemistry, 2009 Vasopressin controls renal water excretion largely through actions to regulate the water channel aquaporin-2 in collecting duct principal cells. Our knowledge of the mechanisms involved has increased markedly in recent years with the advent of methods for large-scale systems-level profiling such as protein mass spectrometry, yeast two-hybrid analysis ...
Jason D, Hoffert +2 more
openaire +2 more sources
Aquaporin-10 represents an alternative pathway for glycerol efflux from human adipocytes. [PDF]
PLoS ONE, 2013 BACKGROUND: Glycerol outflow from adipocytes has been considered for a decade to be mediated by aquaporin-7, an aquaglyceroporin highly expressed in the adipose tissue. Its involvement in glycerol metabolism has been widely studied also in humans. Recent
Umberto Laforenza +2 more
doaj +1 more source
Expression and prognostic value of aquaporin 1, 3 in cervical carcinoma in women of Uygur ethnicity from Xinjiang, China. [PDF]
PLoS ONE, 2014 BACKGROUND: Overexpression of several aquaporins has been reported in different types of human cancer but the role of aquaporins in carcinogenesis has not yet been clearly defined.
Rui Chen +4 more
doaj +1 more source