Results 41 to 50 of about 22,200,369 (327)
Vasopressin–aquaporin-2 pathway: recent advances in understanding water balance disorders
F1000Research, 2019 The alteration of water balance and related disorders has emerged as being strictly linked to the state of activation of the vasopressin–aquaporin-2 (vasopressin–AQP2) pathway.
M. Ranieri +3 more
semanticscholar +1 more source
Trafficking mechanism of water channel aquaporin‐2 [PDF]
Biology of the Cell, 2005 Targeted positioning of the water channel AQP2 (aquaporin‐2) strictly regulates body water homoeostasis. Trafficking of AQP2 to the apical membrane is critical for the reabsorption of water in renal collecting ducts. In addition to the cAMP‐mediated effect of vasopressin on AQP2 trafficking to the apical membrane, other signalling cascades can also ...
Yumi, Noda, Sei, Sasaki
openaire +2 more sources
In vivo imaging of the tonoplast intrinsic protein family in Arabidopsis roots [PDF]
, 2009 Background: Tonoplast intrinsic proteins (TIPs) are widely used as markers for vacuolar compartments in higher plants. Ten TIP isoforms are encoded by the Arabidopsis genome.
Frigerio, Lorenzo +4 more
core +4 more sources
AAPS Journal, 2019 Renal transporters, which are primarily located in the proximal tubules, play an important role in secretion and nephrotoxicity of drugs. The goal of this study was to characterize the age-dependent protein abundance of human renal transporters.
C. Li +5 more
semanticscholar +1 more source
Vasopressin and the regulation of aquaporin-2 [PDF]
Clinical and Experimental Nephrology, 2013 Water excretion is regulated in large part through the regulation of osmotic water permeability of the renal collecting duct epithelium. Water permeability is controlled by vasopressin through regulation of the water channel, aquaporin-2 (AQP2).
Justin L. L. Wilson +2 more
semanticscholar +3 more sources
Increased intestinal carbonate precipitate abundance in the sea bream (Sparus aurata L.) in response to ocean acidification [PDF]
, 2019 Marine fish contribute to the carbon cycle by producing mineralized intestinal precipitates generated as by-products of their osmoregulation. Here we aimed at characterizing the control of epithelial bicarbonate secretion and intestinal precipitate ...
Carvalho, Edison S. M. +3 more
core +1 more source
Cellular Physiology and Biochemistry, 2019 BACKGROUND/AIMS Apelin and its G protein-coupled receptor APJ (gene symbol Aplnr) are strongly expressed in magnocellular vasopressinergic neurons suggesting that the apelin/APJ system plays a key role at the central level in regulating salt and water ...
Chahrazed Boulkeroua +10 more
semanticscholar +1 more source
FEBS Open Bio, 2015 Several point mutations have been identified in human aquaporins, but their effects on the function of the respective aquaporins are mostly enigmatic. We analyzed the impact of the aquaporin 2 mutation V71M, which causesnephrogenic diabetes insipidus in ...
Noreen Klein +3 more
doaj +1 more source
ASN Neuro, 2020 In ischemic stroke, vasopressin hypersecretion is a critical factor of cerebral swelling and brain injury. To clarify neural mechanisms underlying ischemic stroke-evoked vasopressin hypersecretion, we observed the effect of unilateral permanent middle ...
Dan Cui +9 more
doaj +1 more source
Bile Acid G Protein-Coupled Membrane Receptor TGR5 Modulates Aquaporin 2-Mediated Water Homeostasis.
Journal of the American Society of Nephrology, 2018 BACKGROUND The bile acid-activated receptors, including the membrane G protein-coupled receptor TGR5 and nuclear farnesoid X receptor (FXR), have roles in kidney diseases.
Suchun Li +16 more
semanticscholar +1 more source