Results 231 to 240 of about 2,493,291 (257)

Establishment of A Mouse Model of Aqueous Deficiency Dry Eye

Journal of Visualized Experiments
Dry eye disease is a prevalent condition affecting 5%-50% of the global population. Animal model investigations play a crucial role in understanding its underlying mechanisms. Therefore, we developed a mouse model of dry eye disease by surgically removing both the extraorbital lacrimal glands (ELG) and intraorbital lacrimal glands (ILG) to investigate ...
Meng, Zhang, Xiaoyu, Tian, Yiming, Wu, Liying, Zhang, Lingli, Zhang, Xueer, Zheng, Shangkun, Ou, Hao, Gu   +7 more
openaire   +2 more sources

Aqueous-Deficient Dry Eye Disease: Evaluation and Management

2017
This opening chapter describes the evaluation and management of three patients with increasing severity of aqueous-deficient dry eye disease (AD-DED) (the management of meibomian gland disease, which frequently coexists with aqueous deficiency, is discussed in Chap. 2).
Benjamin Botsford, Farhan I. Merali, Samuel C. Yiu   +2 more
openaire   +1 more source

Long-Term Results of Treatment With Diquafosol Ophthalmic Solution for Aqueous-Deficient Dry Eye

Japanese Journal of Ophthalmology, 2013
To evaluate the preliminary long-term efficacy of diquafosol ophthalmic solution for aqueous-deficient dry eye.Fifteen patients with mild-to-moderate aqueous-deficient dry eye were enrolled. After a washout period, the patients were treated with 3 % diquafosol ophthalmic solution for 6 months.
Naoyuki Maeda, Kohji Nishida, Shizuka Koh   +2 more
exaly   +3 more sources

Acupuncture for aqueous deficiency dry eye: a randomized controlled trial.

Zhongguo zhen jiu = Chinese acupuncture & moxibustion, 2023
To compare the clinical efficacy and safety of acupuncture and sodium hyaluronate eye drop in the treatment of aqueous deficiency dry eye.A total of 60 patients (120 eyes) with aqueous deficiency dry eye were randomly divided into an observation group (30 cases, 1 case dropped out) and a control group (30 cases, 1 case dropped out).
Xue, Liu, Wei-Ping, Gao, Nan, Zhao, Rui-Ping, Jie, Cheng-Yong, Liu   +4 more
openaire   +1 more source

The Effect of Punctal Occlusion on Tear Lactoferrin in Aqueous Deficient Dry Eye Patients

2002
Many dry eye patients undergo punctal occlusion to relieve the signs and symptoms of keratoconjunctivitis sicca (KCS). Punctal occlusion inhibits lacrimal fluid loss from the tear film by blocking the naso-lacrimal duct. This improves the symptoms in patients with tear-deficient dry eye, but it is unknown as to whether there is a concomitant ...
Vernon, Reese, Pierce R, Youngbar
openaire   +2 more sources

Distribution of Aqueous-Deficient and Evaporative Dry Eye in a Clinic-Based Patient Cohort

Cornea, 2012
To evaluate in a general clinic-based cohort of patients with dry eye disease (DED) the distribution of patients with aqueous-deficient or evaporative subtype of DED.Schirmer tests and meibomian gland dysfunction (MGD) (Foulks-Bron scoring) were evaluated in both eyes of 299 normal subjects and DED patients (218 women and 81 men) across 10 sites in the
Michael A, Lemp, Leslie A, Crews, Anthony J, Bron, Gary N, Foulks, Benjamin D, Sullivan   +4 more
openaire   +2 more sources

Different Conjunctival Adaptive Response in Patients with Aqueous-Deficient and with Mucous-Deficient Dry Eyes

European Journal of Ophthalmology, 2007
Purpose To describe the different cellular adaptive patterns found in the conjunctival epithelium from patients with aqueous-deficient and mucous-deficient dry eyes. Methods The authors studied different conjunctival areas, by ...
L, Rivas, J S, López-García, J, Murube, I, García-Lozano   +3 more
openaire   +2 more sources

Prevalence and predictors of Sjögren's syndrome in a prospective cohort of patients with aqueous-deficient dry eye

British Journal of Ophthalmology, 2012
To assess the prevalence and determine predictors of Sjögren's syndrome (SS) in patients with clinically significant aqueous-deficient dry eye.Patients enrolled in an industry-sponsored, multicentre clinical trial (NCT00784719) were assessed prospectively for the presence of SS.
Melissa Shiao Hui, Liew, Min, Zhang, Elizabeth, Kim, Esen K, Akpek   +3 more
openaire   +2 more sources

Developing a model for aqueous deficient dry eye secondary to periglandular cicatrizing conjunctivitis

Experimental Eye Research
The current study used various techniques to develop a rabbit animal model of lacrimal gland damage caused by scarring conjunctivitis in the periglandular area.Left eyes of New Zealand white rabbits were injected with 0.1 ml of 1M NaOH subconjunctivally around superior and inferior lacrimal gland orifices (Group 1, n = 4), touched with 1M NaOH for 100 ...
Swati Singh, Saumya Srivastav, Jilu Jaffet, Deeksha Prasad, Khyathi Ratna Padala, Vivek Singh, Kiran Kumar Bokara, Sayan Basu   +7 more
openaire   +2 more sources

Tearful Relationships? Sex, Hormones, the Lacrimal Gland, and Aqueous-Deficient Dry Eye

The Ocular Surface, 2004
Sex and the endocrine system exert a significant influence on the physiology and pathophysiology of the lacrimal gland. The purpose of this article is to briefly review the nature and magnitude of these interactions between sex, hormones and lacrimal tissue, and to address how they may relate to the pathogenesis of aqueous-deficient dry eye.
openaire   +2 more sources