Results 61 to 70 of about 1,452,056 (354)

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner

open access: yesMolecular Oncology, EarlyView.
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp   +13 more
wiley   +1 more source

High‐Performance Thermoelectric SnSe: Aqueous Synthesis, Innovations, and Challenges

open access: yesAdvanced Science, 2020
Tin selenide (SnSe) is one of the most promising candidates to realize environmentally friendly, cost‐effective, and high‐performance thermoelectrics, derived from its outstanding electrical transport properties by appropriate bandgaps and intrinsic low ...
Xiao‐Lei Shi   +3 more
doaj   +1 more source

Aqueous polyvinyl alcohol solution foaming at different molecular masses

open access: yesТонкие химические технологии, 2021
Objectives. Investigation of aqueous polyvinyl alcohol (PVA) foaming process and the influence of its water solution structure, when possessed of different molecular weights and concentrations, on foaming multiplicity.Methods.
A. A. Akimova   +2 more
doaj   +1 more source

Kinetics of Carbon Dioxide with tertiary Amines in aqueous solution [PDF]

open access: yes, 1999
The reaction of CO2 with TEA, DMMEA, and DEMEA has been studied at 293, 303, 318 and 333 K. All the kinetic experiments were carried out in a stirred cell reactor operated with a flat, smooth and horizontal gas-liquid interface. A numerical method, which
Littel, R.J.   +2 more
core   +3 more sources

Spontaneous Chelation-Driven Reduction of the Neptunyl Cation in Aqueous Solution. [PDF]

open access: yes, 2020
Octadentate hydroxypyridinone (HOPO) and catecholamide (CAM) siderophore analogues are known to be efficacious chelators of the actinide cations, and these ligands are also capable of facilitating both activation and reduction of actinyl species ...
Abergel, Rebecca J   +7 more
core   +1 more source

Association of high‐dose radioactive iodine therapy with PPM1D‐mutated clonal hematopoiesis in older individuals

open access: yesMolecular Oncology, EarlyView.
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim   +11 more
wiley   +1 more source

Unveiling unique protein and phosphorylation signatures in lung adenocarcinomas with and without ALK, EGFR, and KRAS genetic alterations

open access: yesMolecular Oncology, EarlyView.
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi   +12 more
wiley   +1 more source

Using Generation 3 Polyamidoamine Dendrimer as Adsorbent for the Removal of Pentavalent Arsenic from Aqueous Solutions

open access: yesJournal of Environmental Health and Sustainable Development, 2016
Introduction: Arsenic is known as a carcinogenic compound in drinking water. It can cause acute and chronic effects on human health. In this study, the effect of polyamidoamine dendrimer generation 3 (PAMAM G3) as adsorbents for removal of arsenic (V ...
Zeynab Yavari   +4 more
doaj  

Sonophotoluminescence from aqueous and non-aqueous solutions

open access: yesUltrasonics Sonochemistry, 1999
The sonoluminescence generated in air-saturated aqueous and non-aqueous solutions using 515 kHz ultrasound has been used to vibronically excite several fluorescent solutes, namely fluorescein, eosin, pyranine and pyrene. Emission, referred to as 'sonophotoluminescence', was generated in situ with emission spectra that closely matched those obtained by ...
Muthupandian Ashokkumar, Franz Grieser
openaire   +3 more sources

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