Results 61 to 70 of about 4,538,204 (253)

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Removal of Direct Red 81 from Aqueous Solution Using an Acidic Soil Containing Iron (Case Study of Lahijan Soil) [PDF]

open access: yesIranian Journal of Chemistry & Chemical Engineering, 2019
Direct Red 81, a dye widely used in textile industries, is frequently detected dye in water resources. High costs, the formation of hazardous byproducts, and high energy costs restrict the use of some removal methods.
Samaneh Shahsavani   +2 more
doaj  

Snow-Ice-Inspired Approach for Growth of Amorphous Silicon Nanotips

open access: yesNanomaterials, 2019
The growth of one-dimensional nanostructures without a metal catalyst via a simple solution method is of considerable interest due to its practical applications.
Seungil Jo, Hyunsoo Kim, Nae-Man Park
doaj   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

Synthesis of metallic aluminum particles by electrolysis in aqueous solution

open access: yesMicro and Nano Systems Letters, 2021
The present work proposes a method for fabricating metallic Al particles in aqueous solution. An aqueous colloidal solution was prepared from an aqueous aluminum nitrate nonahydrate solution by electrolysis using metallic Al plates as the anode and ...
Takefumi Hosoya   +4 more
doaj   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Binding of chloroplast signal recognition particle to a thylakoid membrane protein substrate in aqueous solution and delineation of the cpSRP43–substrate interaction domain [PDF]

open access: yes, 2011
A cpSRP [chloroplast SRP (signal recognition particle)] comprising cpSRP54 and cpSRP43 subunits mediates the insertion of light-harvesting proteins into the thylakoid membrane. We dissected its interaction with a full-length membrane protein substrate in
Colin Robinson   +10 more
core   +1 more source

Prediction of thermal conductivity of aqueous solution at high pressures by using artificial neural network [PDF]

open access: yesChemical Industry and Chemical Engineering Quarterly, 2014
The objective of this study is to predict thermal conductivity of aqueous solution with artificial neural network (ANN) model with three inputs (pressure, temperature and concentration).
Amooey Ali Akbar   +2 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Computing the aqueous solubility of organic drug-like molecules and understanding hydrophobicity [PDF]

open access: yes, 2015
This thesis covers a range of methodologies to provide an account of the current (2010-2014) state of the art and to develop new methods for solubility prediction.
McDonagh, James L.
core   +1 more source

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