Results 191 to 200 of about 16,348 (221)
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Journal of Allergy and Clinical Immunology, 1984
Leukotrienes have potent biologic actions in various biologic systems. Leukotriene (LT) B4 has inflammatory properties and has been detected in exudates from human inflammatory disease including psoriasis. LTC4, LTD4, and LTE4 have potent bronchoconstrictor actions in vitro and in normal human subjects. LTE4 causes very long-lasting bronchoconstriction.
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Leukotrienes have potent biologic actions in various biologic systems. Leukotriene (LT) B4 has inflammatory properties and has been detected in exudates from human inflammatory disease including psoriasis. LTC4, LTD4, and LTE4 have potent bronchoconstrictor actions in vitro and in normal human subjects. LTE4 causes very long-lasting bronchoconstriction.
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Kinetic Studies on Arachidonate 5-Lipoxygenase from Rat Basophilic Leukemia Cells
Biological Chemistry Hoppe-Seyler, 1988Arachidonate 5-lipoxygenase of a 10,000 x g supernatant from RBL-1 cell homogenate was studied by a continuous assay measuring enzyme-catalysed oxygen consumption. Parallel HPLC and TLC analysis of arachidonic acid metabolites revealed that the oxygen consumption measured is solely due to 5-lipoxygenation of arachidonic acid. Oxygen consumption by this
M, Haurand, L, Flohé
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Cerebral Edema Induced by Arachidonic Acid: Role of Leukocytes and 5-Lipoxygenase Products
Neurosurgery, 1989Arachidonic acid is released from cellular phospholipid membranes after brain injury associated with vasogenic edema. Intracerebral injection of arachidonic acid results in rapid breakdown of the blood-brain barrier, followed by an increase in brain water and sodium content.
S M, Papadopoulos, K L, Black, J T, Hoff
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Lipoxin Syntheses by Arachidonate 12- and 5-Lipoxygenases Purified from Porcine Leukocytes
1988Recently, we were successful in the purification of 12-lipoxygenase1 and 5-lipoxygenase2 from porcine leukocytes by immunoaffinity chromatography using their monoclonal antibodies which were raised with the crude enzyme preparations as antigen3, 4. In this chapter the lipoxin biosynthesis will be discussed as catalytic properties of these purified ...
S, Yamamoto +6 more
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Fish & Shellfish Immunology
A number of studies have been demonstrated that arachidonate 5-lipoxygenase (ALOX-5) plays a role in regulating a range of physiological and pathological processes through the catalysis of leukotriene formation from arachidonic acid (ARA). The coding sequence of ALOX-5 from Apostichopus japonicus (Aj-ALOX-5) was successfully amplified, resulting in a ...
Jiahao, Cheng +5 more
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A number of studies have been demonstrated that arachidonate 5-lipoxygenase (ALOX-5) plays a role in regulating a range of physiological and pathological processes through the catalysis of leukotriene formation from arachidonic acid (ARA). The coding sequence of ALOX-5 from Apostichopus japonicus (Aj-ALOX-5) was successfully amplified, resulting in a ...
Jiahao, Cheng +5 more
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[34] Leukocyte arachidonate 5-lipoxygenase: Isolation and characterization
1990Carol A. Rouzer, Bengt Samuelsson
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