Results 51 to 60 of about 10,266 (192)

Infection control in the brain and the eye

Acta Ophthalmologica, EarlyView.
Abstract The Central Nervous System (CNS), comprising the brain and the eye, is considered to have a ‘privileged’ mechanism for dealing with immunological challenge (immune privilege, IP). CNS IP has been revealed through experiments using foreign protein antigens and cell and tissue alloantigens (grafts), but evidence for a role for IP in modulating ...
John V. Forrester, Paul G. McMenamin, Samantha J. Dando   +2 more
wiley   +1 more source

Human brain matters: Navigating the neuropathology of COVID‐19

Brain Pathology, EarlyView.
Severe COVID‐19 is associated with vascular dysregulation and chronic neuroinflammation, leading to axonal injury and neurodegeneration. In long COVID or PASC, persistent alterations in neuroimaging and biofluid biomarkers reflect ongoing neuronal damage and neuroinflammation, contributing to long‐term neurological symptoms including fatigue, cognitive
Juliana M. Nieuwland, Angelica Scaramuzza, Marianna Bugiani, Wilma D. J. van de Berg, Jinte Middeldorp   +4 more
wiley   +1 more source

Recurrence of a symptomatic spinal intradural arachnoid cyst 29 years after fenestration

Journal of International Medical Research, 2019
Symptomatic arachnoid cysts are relatively rare, and no case reports have described recurrence of such cysts almost 30 years after surgery. We herein report a case in which a symptomatic intradural arachnoid cyst recurred 29 years after fenestration of ...
Masahiro Nakahashi, Hiroshi Uei, Yasuaki Tokuhashi   +2 more
doaj   +1 more source

Cancer pain: current practice and emerging targets

British Journal of Pharmacology, EarlyView.
Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye, Marcin Chwistek, Zhiting Gong, Vanessa Uzonwanne, Xiaojie Shi, Arpad Szallasi   +5 more
wiley   +1 more source

In silico prediction of novel effective combinational treatment of chronic pain in individual patients: A joint white paper of the H2020 QSPainRelief consortium

British Journal of Pharmacology, EarlyView.
Abstract Opioids are prescribed widely for chronic pain despite well‐recognised risks and variable long‐term benefit, reflecting the lack of effective alternatives for many patients. Combination therapies offer a promising strategy to enhance efficacy whilst reducing side effects.
André Mouraux, Solenn Gousset, Beltrán Alvarez, Monica Baiula, Wouter Bakker, Andrea Bedini, Monir Bertayli, Divakar Budda, Robert Carr, Elisabetta Cuna, Óscar Díaz, Nina Donner, Jesús Giraldo, Geert‐Jan Groeneveld, Berfin Gülave, David Guydan, Hemme Hijma, Rafael Maldonado, Pedro Renault, Carlos Rinaudo, Jeroen Elaissaiss‐Schaap, Athan Spiros, Sara Stoeber, Petri Takkala, Daan van Valkengoed, Coen van Hasselt, Elizabeth (Liesbeth) CM de Lange   +26 more
wiley   +1 more source

Surgical treatment of postoperative arachnoid cysts, imitating relapse of brain glial tumors

Ukrainian Neurosurgical Journal, 2011
Neurological status and results of surgical treatment of 28 patients with brain arachnoid cysts, earlier been operated because of astrocytomas of brain hemispheres, were analyzed.
Sabir Etibarly, K. Dadashov, E. Novruzov
doaj   +1 more source

Inborn errors of immunity in children with neuroinflammation

Developmental Medicine &Child Neurology, EarlyView.
Abstract Inborn errors of immunity (IEIs), an expanding group of monogenic disorders with diverse clinical manifestations, are increasingly recognized to include neuroinflammatory disease. Examples of diseases included under this umbrella are Aicardi–Goutières syndrome, deficiency of adenosine deaminase 2, familial haemophagocytic lymphohistiocytosis ...
Eppie M Yiu, Dilan Dissanayake, Jessie Cunningham, Helen Branson, Ori Scott, E Ann Yeh   +5 more
wiley   +1 more source

Arachnoid cysts in childhood with endocrinological outcomes

The Turkish Journal of Pediatrics, 2011
Arachnoid cysts are mainly manifested with the consequent neurological disorders. Even though these cysts may interfere in many systems due to their localizations, there is little information concerning their involvement in endocrinological ...
Hasan Onal, Erdal Adal, Atilla Ersen, Olcay Işik, Zerrin Onal, Gülseren Arslan   +5 more
doaj  

Obstruction caused by suprasellar cisterna arachnoid cyst expansion after ventriculoperitoneal shunt in children with hydrocephalus

Pediatric Investigation
Introduction Suprasellar cistern arachnoid cysts are rare non‐neoplastic cystic lesions that represent nearly 1% of all intracranial arachnoid cysts. Symptomatology can vary; small cysts typically do not produce any symptoms, whereas larger cysts may ...
Dapeng Li, Wenping Ma, Ming Ge, Di Zhang
doaj   +1 more source

Competitive Interactions Between Generalist Predators and Their Effects on Shared and Non‐Shared Pests in a Greenhouse Crop

Entomologia Experimentalis et Applicata, EarlyView.
Orius laevigatus engages in unidirectional intraguild predation on Transeius montdorensis. Despite this, both predators coexisted and suppressed the shared thrips prey. Aphids, a non‐shared prey, were effectively controlled by O. laevigatus even when its population was limited due to intraguild predation. T.
Angelos Mouratidis, Jesica Pérez‐Rodríguez, Hessel van der Heide, Gerben J. Messelink   +3 more
wiley   +1 more source