Results 171 to 180 of about 51,311 (264)

Gene Correction Enhances Dopaminergic Cell Therapy in a Nonhuman Primate Model of Parkinson's Disease

Advanced Science, EarlyView.
LRRK2‐mutant induced pluripotent stem cells (iPSCs) were derived from a patient with Parkinson's disease (PD). Using CRISPR/Cas9–mediated gene editing, the pathogenic LRRK2 mutations were precisely corrected, and isogenic dopaminergic neural progenitor cells (DA‐NPCs) were subsequently generated.
Qing Yan, Chongchong Xu, Jiangmei Gao, Pu Wang, Qingling Wu, Ying Jin, Binyan Lu, Mu Li, Mingting Shao, Bihai Li, Zhenghui Su, Yijng Zhang, Jianhuan Chen, Haojie An, Mengyao Huang, Xiaoji Zhuang, Yuhui Shen, Fenglin Wang, Nana Xu, Yiyan Liu, Lei Tang, Xiuling Zhong, Minyan Zhong, Jiecong Chen, Zhenhuang Wang, Xingrong Luo, Sheng Liu, RuiFeng Liu, Ling Zhang, Junhua Rao   +29 more
wiley   +1 more source

Spatially multiplexed random-access Raman probe for in vivo tissue measurements. [PDF]

Biomed Opt Express
Sakata W, Fujihara A, Ota T, Harada Y, Smith NI, Ueda T, Takamatsu T, Ukimura O, Fujita K, Kumamoto Y.   +9 more
europepmc   +1 more source

Chemically Gradient Ordered Nanodomains Enable Large Tensile Ductility in Gigapascal Lightweight Refractory High‐Entropy Alloys

Advanced Science, EarlyView.
A high‐strength lightweight refractory high‐entropy alloy achieves extraordinary ductility owing to the introduction of coherent chemically gradient ordered nanodomains (CGONs). The CGONs not only serve as effective barriers to dislocation motion (strengthening) but also significantly promote dislocation nucleation and multiplication (ductilizing) upon
Wei Zhang, Dingshun Yan, Yong Zhang, Zhiming Li   +3 more
wiley   +1 more source

Multicolor Emission in Perovskite Nanostructures via Quantum Confinement Engineering for High-Speed Optical Wireless Communication. [PDF]

ACS Nano
Zhu X, Niu W, Wang L, Hu X, Zhou R, Wang JX, Li X, Ng TK, Alshareef HN, Bakr OM, Ooi BS, Mohammed OF.   +11 more
europepmc   +1 more source

Label‐Free Myelin Fingerprinting: An Adult Human Post‐Mortem Brain Slice Platform via Coherent Anti‐Stokes Raman Spectroscopy

Advanced Science, EarlyView.
A serum‐free, air–liquid interface organotypic slice culture model preserves human post‐mortem corpus callosum tissue, successfully recovering from slicing trauma to reflect the donor's underlying disease state. Pairing label‐free Coherent anti‐Stokes Raman scattering (CARS) microscopy with k‐means clustering enables objective, high‐resolution ...
Kasra Roya‐Kouchaki, Jeroen P. Korterik, Femke Tjebbes, Geert J. Schenk, Herman L. Offerhaus, Antonio Luchicchi   +5 more
wiley   +1 more source

Electrically reconfigurable extended lasing state in an organic liquid-crystal microcavity. [PDF]

Nat Commun
Dovzhenko D, Ricco LS, Sawicki K, Muszyński M, Kokhanchik P, Kapuściński P, Morawiak P, Piecek W, Nyga P, Kula P, Solnyshkov D, Malpuech G, Sigurðsson H, Szczytko J, De Liberato S.   +14 more
europepmc   +1 more source

Modified MXene Aerogel With Broadband Microwave Absorption Inspired by Melanophila Acuminata Beetle

Advanced Science, EarlyView.
This work introduces a novel biomimetic strategy inspired by the infrared‐sensing sensilla of the Melanophila acuminata beetle. We have designed a multi‐level aerogel, featuring a three‐dimensional carbon framework decorated with synergistic CeO2 nanoparticles and Ti3C2Tx MXene nanosheets.
Zhiwei Liu, Dingyu Xu, Zhaobo Liu, Haitian Song, Qianqian Zhang, Junxiao Zhou, Xiewen Wen   +6 more
wiley   +1 more source

Evaluation of cavitation enhancements in low-boiling point (< -2°C) perfluorocarbon nanodroplet and microbubble mixtures using therapeutic ultrasound pulses. [PDF]

Ultrason Sonochem
Khan H, Dayton PA, Xu Z, Jiang X, Kim J.
europepmc   +1 more source

Enhanced Antibacterial Properties of Lyotropic Liquid Crystalline Nanoparticles via Curvature Modulation

Advanced Science, EarlyView.
Lipid nanostructured particles with increasing negative Gaussian curvature progress from vesicles to P‐cubosomes and D‐cubosomes. This curvature hierarchy enhances interaction with bacterial membranes, promotes membrane remodeling and leakage, and potentiates daptomycin activity against MRSA.
Xiangfeng Lai, Shuhong Wang, Chenguang Ding, Xenia Kostoulias, Anton P. Le Brun, Hsien‐Yi Hsu, Jhih‐Hang Jiang, Yajun Wang, Richard A. Strugnell, Anton Y. Peleg, Hsin‐Hui Shen   +10 more
wiley   +1 more source

Ultra-coherent meta-emitter tailors arbitrary thermal wavefront. [PDF]

Nat Commun
Chen R, Chen T, Liu M, Liu X, Zhang S, Raza F, Dong H, Dang Y, Yu Z, Hu H, Xu J, Qiu CW, Ma Y.   +12 more
europepmc   +1 more source