Results 151 to 160 of about 123,827 (273)

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

FEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori, Kohei Kawabata, Takanori Kubo, Takeo Kitazawa, Sae Kanai, Madoka Iwashita, Ami Hayashi, Hiroyuki Nishi, Mikihisa Takano   +8 more
wiley   +1 more source

The adaptive tasks and trade-offs that drive the human value system. [PDF]

Commun Psychol
Markovitch N, Hilman Amir D, Zer Kavod R, Knafo-Noam A, Hart Y.   +4 more
europepmc   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Connecting Visual Perception With Proton Therapy-Induced Optic Damage Using Archetypal Analysis. [PDF]

Int J Part Ther
Pham TN, Mathis T, Azemar N, Seraphim M, Moignier C, Quintyn JC, Thariat J.   +6 more
europepmc   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

Dual-Level Pattern Tree for Visual Field Improves Glaucoma Progression and Polygenic Risk Prediction. [PDF]

Transl Vis Sci Technol
Song L, Shen LQ, Pasquale LR, Boland MV, Wellik SR, De Moraes CG, Segre A, Wiggs JL, Turman C, Myers JS, Elze T, Zebardast N, Friedman DS, Kang JH, Wang M.   +14 more
europepmc   +1 more source

Writing Over The Maple Leaf: Reworking the Colonial Native Archetype in Contemporary Canadian-Native Literature [PDF]

, 2013
Coleman, John
core   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Divergent oncogenic signaling and immune microenvironment changes in low-grade serous ovarian cancer patients undergoing intraperitoneal chemotherapy. [PDF]

NPJ Precis Oncol
Bishara I, Cosgrove PA, Majumdar S, Egelston CA, Flores OC, Nakamura B, Ruel N, Frankel PH, Yost SE, Chang S, Jung A, Cristea M, Raoof M, Bild AH, Nath A, Dellinger TH.   +15 more
europepmc   +1 more source

The Archetype [PDF]

, 1971
Koertge, Ronald
core