Five archetypes of small-scale fisheries reveal a continuum of production strategies to guide governance and policymaking. [PDF]
Aguión A +6 more
europepmc +1 more source
Structural and regulatory determinants of flagellar motility in Rhodobacterales – The archetypal flagellum of Phaeobacter inhibens DSM 17395 [PDF]
Jürgen Tomasch +9 more
openalex +1 more source
Autophagosome marker, LC3, is released extracellularly via several distinct pathways
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito +3 more
wiley +1 more source
Basing healthcare decisions on value: patient-reported outcomes for patients diagnosed with breast cancer in a European cohort. [PDF]
Gorostiza A +16 more
europepmc +1 more source
Analysis of Treacher Collins syndrome 4‐associated mutations in Schizosaccharomyces pombe
Fission yeast models carrying Treacher Collins syndrome type 4‐associated mutations reveal that impaired processivity of RNA polymerase I leads to defective rRNA transcription. This study highlights the essential role of a conserved arginine residue in Pol I elongation and provides mechanistic insight into the pathogenesis of ribosomopathies.
Kei Kawakami, Hiroaki Kato
wiley +1 more source
Normalizing toxicity: the role of recommender algorithms for young people's mental health and social wellbeing. [PDF]
Regehr K +5 more
europepmc +1 more source
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima +4 more
wiley +1 more source
ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori +8 more
wiley +1 more source
Higher diversity and abundance of microRNA-455-5p isoforms confer suppressive role in Wilms' tumor. [PDF]
Chen C +6 more
europepmc +1 more source

