Results 171 to 180 of about 23,270 (281)

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

The Nature of a Recently Discovered Wolf-Rayet Binary: Archetype of Stripping? [PDF]

Philip Massey, Kathryn F. Neugent, N. Morrell, D. J. Hillier, Laura R. Penny   +4 more
openalex   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

The ARCH model: a neuroevolutionary framework for behavioral execution. [PDF]

Front Psychiatry
Rahman T, Zorumski CF, Meloy JR.
europepmc   +1 more source

CLIP-Guided Clustering with Archetype-Based Similarity and Hybrid Segmentation for Robust Indoor Scene Classification [PDF]

Emi Yuda, Naoya Morikawa, Itaru Kaneko, Daisuke Hirahara   +3 more
openalex   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Metabolism archetype cancer cells induce protumor TREM2⁺ macrophages via oxLDL-mediated metabolic interplay in hepatocellular carcinoma. [PDF]

Nat Commun
Chu T, Zhu G, Tang Z, Qu W, Yang R, Pan H, Wang Y, Tian R, Chen L, Guan Z, Bu Y, Zhao Q, Chen J, Mao S, Fang Y, Gao J, Wu X, Zhou J, Liu W, Ye D, Fan J, Shi Y.   +21 more
europepmc   +1 more source

Integration of tools for binding archetypes to SNOMED CT [PDF]

, 2008
Erik Sundvall, Rahil Qamar, Mikael Nyström, Mattias Forss, Håkan Petersson, Daniel Karlsson, Hans Åhlfeldt, Alan Rector   +7 more
openalex   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Tropical dry woodland loss in India since 1880 and its relation to current megafauna distributions. [PDF]

Ecol Appl
Kalam T, Baumann M, Pötzschner F, Reddy CS, Ghoddousi A, Roy PS, Kuemmerle T.   +6 more
europepmc   +1 more source