Results 71 to 80 of about 174,245 (292)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Architects/City Planners in the Peace Corps [PDF]
, 1966 Graduate architects and city planners have been requested by the Governments of Tunisia and Colombia to assist in their high priority housing programs.
American Institute of Architects
core
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Architectes cinéastes, cinéastes architectes
Calenda, 2015 Ces deux journées d’études ont pour but d’aborder deux figures hybrides de la création contemporaine : l’architecte-cinéaste et le cinéaste-architecte. L’influence du cinéma sur la pensée et la création en architecture, l’appréhension et l’intégration du dispositif et de l’écriture cinématographique par l’architecte méritent d’être réévaluées, ainsi ...
openaire +3 more sources
Проект Байкал, 2015 After Brezhnev’s death, starting from 1983, there were troublesome times in Russia. At first the senile secretaries general came and passed away, making ‘a funeral parade’, and then Gorbachev’s perestroika started.
Vladimir Stegaylo +4 more
doaj +1 more source
Doctor Watson Architects: Classic AIR Grid, Collection
, 2018 Teams of architects were subjected to prolonged exposure to Miesian space, resulting in the discovery of the AIR Grid. Although the sparse, reductive architectures of Mies van der Rohe are mute to the media of photography and architectural drawing they ...
Watson, V.A.
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Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Journal of Asian Architecture and Building EngineeringLearning Commons is being actively implemented in the design of university buildings to encourage diverse learning. Because the usage patterns of Learning Commons are different from those of regular classrooms, this design trend also has a significant ...
Yuma Tokuwaki +4 more
doaj +1 more source
Penn State Dickinson School of Law, Lewis Katz Building
, 2009 aerial view, Penn State's Dickinson School of Law opened its new 114,000-square-foot Lewis Katz Building, a sinuous, glass-clad structure designed by New York City-based Polshek Partnership Architects renamed Ennead Architects. The Lewis Katz Building is
Ennead Architects
core
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source