Results 141 to 150 of about 568,927 (343)
Addressing cultural, social and environmental sustainability in architecture. The approach of five contemporary Australian architects [PDF]
, 2007 Regionalist architecture offers a promising and conscientious response to the present scenario of growing trend toward cultural, social and technical globalization.
Paolella, A, Quattrone, G
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Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Involvement of People in the Design of Community Building in Developing Countries [PDF]
, 2013 Although public participation concept or technique to enhance and /or influence decision making is a fact of life in many governments nowadays and has been used by many industries to improve their products and increase end-users satisfaction, it is still
Alalem, Mohamed +2 more
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Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Comparative studies of offices pre and post — how changing spatial configurations affect organisational behaviours [PDF]
, 2009 Understanding the way in which design interventions in an office affect everyday users, and thus shape organisational behaviour, should be high on the agenda for architects, designers and consultants alike. Surprisingly, this seems rarely to be the case.
Budgen, A. +4 more
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Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Architects and Information Architects [PDF]
Bulletin of the American Society for Information Science and Technology, 2000 openaire +1 more source
CESEC Chair – Training Embedded System Architects for the Critical Systems Domain [PDF]
, 2013 Increasing complexity and interactions across scientific and tech- nological domains in the engineering of critical systems calls for new pedagogical approach. In this paper, we introduce the CESEC teaching chair.
Cardoso, Janette, Hugues, Jérôme
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Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Forced Migration Review, 2017 Most families recovering from the catastrophe of a disaster rebuild their own homes. This practice of self-recovery by non-displaced communities has potential for displaced populations too.
Bill Flinn +2 more
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