Results 141 to 150 of about 175,316 (291)
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Gordon Wittenberg Arkansas architects collection
, 1870 This collection contains photocopies of material collected in research conducted by Wittenberg on the lives and work of architects in Arkansas, generally from the middle of the 19th century through the middle of the 20th ...
Wittenberg, Gordon, 1922-
core +1 more source
Thriving spaces: greening refugee settlements
Forced Migration Review, 2017 By incorporating urban agriculture initiatives within refugee camp settings, the concept of shelter can be expanded to include providing protection from the climate, addressing nutritional deficiencies and increasing levels of human dignity, place making
Carrie Perkins +2 more
doaj
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Layered Development of Visual Search Expertise in Architects. [PDF]
J Eye Mov ResIvy S +3 more
europepmc +1 more source
Four Seasons Centre for the Performing Arts
, 2003 West elevation, frontal view; The Four Seasons Centre for the Performing Arts is a 2,043-seat theatre in Toronto, Ontario, Canada which had its grand opening Wednesday, June 14, 2006.
Diamond + Schmitt Architects, Inc.
core
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Nubanusit Neighborhood and Farm
, 2009 aerial view, Nubanusit Neighborhood & Farm: a family-friendly cohousing community with homes that are 'green' - environmentally designed, quality built, and super energy-efficient, and clustered along pedestrian ways adjacent to their farm fields and the
O'Neil Pennoyer Architects
core
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source