Results 61 to 70 of about 124,140 (299)
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Doctor Watson Architects: Classic AIR Grid, Collection
, 2018 Teams of architects were subjected to prolonged exposure to Miesian space, resulting in the discovery of the AIR Grid. Although the sparse, reductive architectures of Mies van der Rohe are mute to the media of photography and architectural drawing they ...
Watson, V.A.
core
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Architecting for Sustainability.
, 2022 Sustainability is becoming an increasingly important topic. Information Technology (IT) is an important factor for sustainability; it consumes a substantial, and growing, part of the world supply of energy, but it can also enable significant insights and improvements related to sustainability.
Lago, Patricia +2 more
openaire +2 more sources
, 2021 Architecture, at its core, is both an art and a science—the art of envisioning spaces and the science of realising them through thoughtful design. As a multidisciplinary field, architecture is influenced by a wide array of factors, from aesthetics and technology to economics and society. Among these, one of the most significant—and often underestimated—
openaire +2 more sources
Anti-Vitruvian architects and contemporary society
, 2011 Certain issues keep presenting themselves on the map of discussions about architecture and its role as a profession in contemporary societies. Recently, I came across two web interventions that highlight some of these issues. The first is a video clip on
Salama, Ashraf M
core
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
AI & SOCIETY, 2010 From the grotesque pavilions hidden in sixteenth century Italian gardens to the temporary structures in public space in the 70s and recent digitally augmented environments, architectures of play have long been designed to engage explorative experiences.
openaire +1 more source
Penn State Dickinson School of Law, Lewis Katz Building
, 2009 aerial view, Penn State's Dickinson School of Law opened its new 114,000-square-foot Lewis Katz Building, a sinuous, glass-clad structure designed by New York City-based Polshek Partnership Architects renamed Ennead Architects. The Lewis Katz Building is
Ennead Architects
core
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source