Results 51 to 60 of about 175,316 (291)

Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin, Sheila K. Pierson, Kelley C. Dacus, Mateo Sarmiento Bustamante, Saishravan Shyamsundar, Larissa Borys, Kayla McHugh, Abiola Irvine, Yoojin Jo, Adam Bagg, Mary Jo Lechowicz, Daisy Alapat, Amy Chadburn, Megan S. Lim, Gordan Srkalovic, Frits van Rhee, David C. Fajgenbaum, Joshua D. Brandstadter   +17 more
wiley   +1 more source

The Impact of the COVID‐19 Pandemic on Childhood Cancer Survival: A Population‐Based Assessment of Survival Patterns Between 2015 and 2023 in Germany

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Numerous international studies have reported declines in new cancer diagnoses, delayed diagnoses and disruptions in cancer treatment following the implementation of COVID‐19 pandemic public health measures, raising concerns that these effects may ultimately contribute to increased cancer mortality.
Friederike Erdmann, Maike Wellbrock, Javier Louro, Arndt Borkhardt, Martin Schrappe, Claudia Trübenbach, Desiree Grabow, Cécile M. Ronckers, Joachim Schüz   +8 more
wiley   +1 more source

Referral Patterns and Diagnostic Timeliness in Pediatric Cancer: A Hospital‐Based Study in Indonesia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Timely diagnosis and treatment are critical for improving survival among children with cancer. In low‐ and middle‐income countries (LMICs), delays are common and may be influenced by fragmented referral pathways and diagnostic limitations.
Nur Melani Sari, Regina Hadi Putri, Fatimah Assyifa, Judith Spijkerman, Gertjan Johannes Kaspers, Susi Susanah   +5 more
wiley   +1 more source

Renovation of Kiyotsu Gorge Tunnel—A Case Study on the Effect of the Combination of Visual Information and Environmental Grade in a Sequential Space on Human Psychological Response

Japan Architectural Review
This project is based on the hypothesis that the combination of visual information and environmental grades—such as airflow and temperature—in a uniform, sequential space can influence psychological responses.
Yosuke Hayano, Ma Yansong, Dang Qun, Jun Nakagawa   +3 more
doaj   +1 more source

La recherche sur les acteurs de la fabrication de la ville : coulisses et dévoilements

Territoire en Mouvement, 2019
In urban research, the analysis of actors and manufacturing processes in the city has an intermittent presence and visibility. After the wave of Marxist-inspired works on the production of the capitalist city, circumscribed in the 1970s, then the ...
Véronique Biau
doaj   +1 more source

Understanding the Legendary Sound Environment in the Lobby of Hotel Okura Tokyo

Applied Sciences, 2020
The main lobby of Hotel Okura Tokyo has a good reputation for its sound environment, which affects the conversations of its users. We assumed that the lobby’s reputation was related to its speech intelligibility.
Ryoko Nojima, Natsuko Sugie, Akira Taguchi, Jun Kokubo   +3 more
doaj   +1 more source

Venetoclax‐Based Therapy as a Bridge to Hematopoietic Stem Cell Transplantation in Relapsed or Refractory Pediatric Acute Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Relapsed and/or refractory (R/R) pediatric acute leukemia carries a dismal prognosis, largely driven by chemoresistance to conventional salvage therapy. The BH3‐mimetic venetoclax, combined with chemotherapy or hypomethylating agents, has demonstrated efficacy in small clinical trials.
Katherine S. Colman, Deborah Meyran, Vajiranee Malalasekera, Heather Weerdenburg, Janine Campbell, Rachel Conyers, Stacie Wang, Hannah Walker, Seong Lin Khaw, Diane Hanna   +9 more
wiley   +1 more source

Learning from school buildings: energy efficiency and user comfort in Metro Vancouver elementary schools

FACETS
In this study, schools built after 2000 in Metro Vancouver, Canada, showed an encouraging trend towards lower carbon emissions and energy use intensity. In 17 case studies, heat pumps, decentralized ventilation systems, and higher glazing-to-wall ratios ...
Amalie Lambert, Marie-Odile Marceau, Michael Hammock, Jonathan Ho   +3 more
doaj   +1 more source

The Architect and the Law

, 2021
Architecture, at its core, is both an art and a science—the art of envisioning spaces and the science of realising them through thoughtful design. As a multidisciplinary field, architecture is influenced by a wide array of factors, from aesthetics and technology to economics and society. Among these, one of the most significant—and often underestimated—
openaire   +2 more sources

Language, Culture, and Cancer: Qualitative Insights Into Communication Disparities Among Spanish‐Speaking Caregivers of Children With Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Latino children are projected to make up nearly one‐third of United States (US) children by 2060, and many of their caregivers speak Spanish. Prior survey research has documented communication difficulties for Spanish‐speaking caregivers of children with cancer, but contemporary qualitative data are limited.
Jenny Ruiz, Alejandra Curbelo‐Paz, Sonia Morales, Elizabeth Contreras, Amy Houtrow, Scott H. Maurer, Judy C. Chang   +6 more
wiley   +1 more source