Results 41 to 50 of about 1,648,705 (255)
The Architectural year book, University of Illinois. 15 [PDF]
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We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Immigration, Disability and Healthcare Access in Brazil
Immigration and refugee status protection are growing phenomena in Brazil and the city of São Paulo is one of the largest hubs in the country for this heterogeneous population. Various studies reveal barriers faced by immigrants and refugees in Brazil to
Samantha Serrano, Denise Martin
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Alzheimer's disease (AD) changes a person's relationship with space. While research exists on how an interactive therapeutic environment can enhance the quality of life for people with Alzheimer's disease (PWAD), PWADs as end-users are not ...
Heidi Elnimr
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
TODAY'S CITIES: CHALLENGES FOR REHABILITATION NURSES FOR INCLUSION
The architectural barriers on public highway cause inaccessibility, contributing to the limitation of functionality and creation of disability. Objectives: to analyze the conditions of accessibility on public highways in view of the needs of disabled ...
Ana Isabel Ribeiro Da Silva Pereira +5 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
News : Colloquium, 13 - 14 september 2022 : Architectural criticism, Medias and Memory
ARCHITECTURAL CRITICISM, MEDIAS AND MEMORY is a colloquium to be held on 13‒14 September 2022 at the office of the Council of Architecture and Urbanism, Rio de Janeiro session (CAU-RJ).
Mapping Architectural Criticism
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