Results 81 to 90 of about 12,219 (259)

Accessibility in the Smart City

TeMA: Journal of Land Use, Mobility and Environment, 2014
FIABA is a cultural route for all, its aim is to promote a Global Accessibility and a Universal Usability through the removal of architectural, cultural, psychological and sensory barriers.
Giuseppe Trieste, Silvia Gabrielli
doaj   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

An assessment of adaptation of Cracow’s cultural institutions to the needs of wheelchair users

Advances in Rehabilitation, 2020
Aneta Bac, Karolina Kowal, Paulina Aleksander-Szymanowicz, Katarzyna Filar-Mierzwa, Edyta Janus   +4 more
doaj   +1 more source

The Architectural Barriers in Living Activies of the Disabled

Eurasian Journal of Medicine, 2019
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Gülten Mert
doaj  

Architects’ Perception of Quality of Life—Impact, Practice, and Barriers

Architecture
This study intended to identify the perception of quality of life (QoL) among architects, how architecture can impact QoL, and which barriers architects perceive to impact QoL. Numerous studies have emphasized the significance of the built environment in
Stine Lea Jacobi, Thomas Bjørner
doaj   +1 more source

Accessibility as a “Key Enabling Knowledge” to Human Development: the Accessibility Plan

Techne, 2014
In Italy, according to Law no. 41/1986 and Law no. 104/1992, public entities must draw up a Plan for Elimination of Architectural Barriers (PEBA). Unfortunately, many years after the introduction of these laws we can see that the PEBA is not yet a ...
Antonio Laurìa
doaj   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Architectural Anatomy and Application in an Ultra-Low-Permeability Reservoir: A Case Study from the Huang 57 Area, Jiyuan Oilfield

Applied Sciences
Reservoir architecture significantly influences fluid flow in ultra-low permeability reservoirs, yet this critical factor is frequently neglected in development strategies.
Lixin Wang, Yanshu Yin, Xinyu Wang, Pengfei Xie, Xun Hu, Ge Xiong   +5 more
doaj   +1 more source