Results 61 to 70 of about 1,570,621 (298)

The Architectural year book, University of Illinois. 9 [PDF]

open access: yes, 1911
None issued 1918-1920 inclusive.Published -1917 by the Architectural Club; 1921- by the Architectural ...

core   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

The Architectural year book, University of Illinois. 4 [PDF]

open access: yes, 1911
None issued 1918-1920 inclusive.Published -1917 by the Architectural Club; 1921- by the Architectural ...

core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Actors and Vehicles of Architectural Criticism (2)

open access: yes, 2016
The Role of Architectural Journals between Medium and the Message Jasna Galjer University of Zagreb The paper explores the case studies of the professional journals in the context of promoting new architectural language and their multilayered roles; from
Mapping Architectural Criticism
core   +1 more source

Barriers to BIM Adoption in Design Practice: A Systematic Review of Developing Countries

open access: yesNature: National Academic Journal of Architecture
Despite the progress made with BIM integration into the construction industries of many developed countries, its adoption remains limited in most developing countries.
Daniel Ebo Hagan   +2 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

The Architectural year book, University of Illinois. 15 [PDF]

open access: yes, 1911
None issued 1918-1920 inclusive.Published -1917 by the Architectural Club; 1921- by the Architectural ...

core   +1 more source

The Architectural year book, University of Illinois. 7 [PDF]

open access: yes, 1911
None issued 1918-1920 inclusive.Published -1917 by the Architectural Club; 1921- by the Architectural ...

core   +1 more source

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